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Literature DB >> 5793242

Induction in vitro of microtubular crystals by vinca alkaloids.

K G Bensch, R Marantz, H Wisniewski, M Shelanski.

Abstract

The addition of vinblastine or vincristine to solutions of pure microtubule protein or to supernatants from high-speed centrifugation of rabbit-brain homogenates results in the formation of a fine precipitate. Examination of this precipitate by electron microscopy reveals ordered structures with areas of ladder-like configuration.

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Year: 1969 PMID： 5793242 DOI： 10.1126/science.165.3892.495

Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728

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Cited

27 in total

1. Postsynaptic scaffolds of excitatory and inhibitory synapses in hippocampal neurons: maintenance of core components independent of actin filaments and microtubules.

Authors: D W Allison; A S Chervin; V I Gelfand; A M Craig
Journal: J Neurosci Date: 2000-06-15 Impact factor: 6.167

2. The role of microtubules in the assembly of vinblastine-induced crystals.

Authors: H Stebbings
Journal: Cell Tissue Res Date: 1975-05-27 Impact factor: 5.249

3. The effect of antimicrotubule agents on the growth and ultrastructure of the fungus Saprolegnia ferax and their ineffectiveness in disrupting hyphal microtubules.

Authors: I B Heath
Journal: Protoplasma Date: 1975 Impact factor: 3.356

4. Flavivirus infection: essential ultrastructural changes and association of Kunjin virus NS3 protein with microtubules.

Authors: M L Ng; S S Hong
Journal: Arch Virol Date: 1989 Impact factor: 2.574

5. Bio-inspired synthesis yields a tricyclic indoline that selectively resensitizes methicillin-resistant Staphylococcus aureus (MRSA) to β-lactam antibiotics.

Authors: Jessica D Podoll; Yongxiang Liu; Le Chang; Shane Walls; Wei Wang; Xiang Wang
Journal: Proc Natl Acad Sci U S A Date: 2013-09-09 Impact factor: 11.205

Induction in vitro of microtubular crystals by vinca alkaloids.

1. Postsynaptic scaffolds of excitatory and inhibitory synapses in hippocampal neurons: maintenance of core components independent of actin filaments and microtubules.

2. The role of microtubules in the assembly of vinblastine-induced crystals.

3. The effect of antimicrotubule agents on the growth and ultrastructure of the fungus Saprolegnia ferax and their ineffectiveness in disrupting hyphal microtubules.

4. Flavivirus infection: essential ultrastructural changes and association of Kunjin virus NS3 protein with microtubules.

5. Bio-inspired synthesis yields a tricyclic indoline that selectively resensitizes methicillin-resistant Staphylococcus aureus (MRSA) to β-lactam antibiotics.

6. Vinblastine-induced precipitation of phloem proteins in vitro.

7. Relationship of nuclear membranes with filaments and microtubules.

8. Synthesis and some properties of an actin-like nuclear protein in the slime mold Physarum polycephalum.

9. Retinal and optic nerve atrophy induced by intravitreous vincristine in the primate.

10. Differential in vitro action of S-12363, a new vinblastine derivative, and of its epimer on microtubule proteins.