Literature DB >> 57895

Alpha-fetoprotein and albumin produced by subclonal cell population of the ascites hepatoma AH-66 in vitro.

H Isaka, S Umehara, H Yoshii, Y Tsukada, H Hirai.   

Abstract

Subclonal cell populations were prepared from a clonal line of the rat ascites hepatoma AH-66 in vitro, using the agar plate culture method. alpha-Fetoprotein and albumin concentrations in culture media of these subclones were determined by 125I-radioimmunoassay and single radial immunodiffusion method, respectively. Results demonstrated that the AH-66 clone was a complex of cells with varying producibility of alpha-fetoprotein and albumin. All the subclones showed varied and distinct production of alpha-fetoprotein, but not all the subclones produced detectable levels of albumin.

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Year:  1976        PMID: 57895

Source DB:  PubMed          Journal:  Gan        ISSN: 0016-450X


  4 in total

1.  Immunoradioautographic study of alpha-fetoprotein in hepatoma cells.

Authors:  T Suganuma; M Koura; H Isaka; Y Tsukada; F Murata
Journal:  Histochemistry       Date:  1980

2.  Effect of a conjugate of daunomycin and antibodies to rat alpha-fetoprotein on the growth of alpha-fetoprotein-producing tumor cells.

Authors:  Y Tsukada; W K Bischof; N Hibi; H Hirai; E Hurwitz; M Sela
Journal:  Proc Natl Acad Sci U S A       Date:  1982-01       Impact factor: 11.205

3.  Chemotherapy by intravenous administration of conjugates of daunomycin with monoclonal and conventional anti-rat alpha-fetoprotein antibodies.

Authors:  Y Tsukada; E Hurwitz; R Kashi; M Sela; N Hibi; A Hara; H Hirai
Journal:  Proc Natl Acad Sci U S A       Date:  1982-12       Impact factor: 11.205

4.  A targeting model of boron neutron-capture therapy to hepatoma cells in vivo with a boronated anti-(alpha-fetoprotein) monoclonal antibody.

Authors:  H Yanagië; Y Fujii; M Sekiguchi; H Nariuchi; T Kobayashi; K Kanda
Journal:  J Cancer Res Clin Oncol       Date:  1994       Impact factor: 4.553

  4 in total

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