| Literature DB >> 578437 |
Abstract
The antitumor agents adriamycin and daunomycin inhibit Ca2+-transport in mitochondria from Ehrlich ascites carcinoma cells as well as in a biphasic model system. The experimental results indicate that both antibiotics interact with phospholipids. The significance of these observations in the pharmacological behavior of these anticancer compounds is discussed.Entities:
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Year: 1977 PMID： 578437
Source DB: PubMed Journal: Arzneimittelforschung ISSN： 0004-4172