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Literature DB >> 5780433

Further study into obstructive jaundice and ischaemic renal damage.

Abstract

Renal ischaemia for one hour in two groups of Gunn rats, one with and the other without bile-duct ligation, produced comparable reversible renal tubular lesions in both groups. Since Gunn rats have an unconjugated hyperbilirubinaemia, which is unaffected by bile-duct ligation, it seems likely that the high levels of bilirubin glucuronide are responsible for sensitizing the renal tubules to ischaemia, possibly by depressing cell respiration.

Entities: Chemical Disease Species

Mesh：

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Year: 1969 PMID： 5780433 PMCID： PMC1983124 DOI： 10.1136/bmj.2.5651.229

Source DB: PubMed Journal: Br Med J ISSN： 0007-1447

12 in total

1. PROTECTIVE EFFECT OF MANNITOL ON ANOXIC JAUNDICED KIDNEYS; A HISTOLOGICAL STUDY.

Authors: J L DAWSON; G A STIRLING
Journal: Arch Pathol Date: 1964-09

2. DIALYSABILITY OF CONJUGATED BILIRUBIN FROM PLASMA OF JAUNDICED DOGS AND PATIENTS.

Authors: M FULOP; J SANDSON; P BRAZEAU
Journal: Lancet Date: 1964-05-09 Impact factor: 79.321

3. The effect of hypotension in obstructive jaundice.

Authors: R D WILLIAMS; D W ELLIOTT; R M ZOLLINGER
Journal: Arch Surg Date: 1960-08

4. Studies on kernicterus; relationship with sulfonamide intoxication, report on kernicterus in rats with glucuronyl transferase deficiency and review of pathogenesis.

Authors: W A BLANC; L JOHNSON
Journal: J Neuropathol Exp Neurol Date: 1959-01 Impact factor: 3.685

5. Constitutional nonhemolytic hyperbilirubinemia in the rat: defect of bilirubin conjugation.

Authors: J V CARBONE; G M GRODSKY
Journal: Proc Soc Exp Biol Med Date: 1957-03

6. Bilirubin, an uncoupler of oxidative phosphorylation in isolated mitochondria.

Authors: L ERNSTER; R ZETTERSTROM
Journal: Nature Date: 1956-12-15 Impact factor: 49.962

7. The effect of bile acids and renal ischemia on renal function.

Authors: T Aoyagi; L M Lowenstein
Journal: J Lab Clin Med Date: 1968-04

8. Red cell survival in experimental cholestatic cholestatic jaundice.

Authors: L W Powell; M A Dunnicliff; B H Billing
Journal: Br J Haematol Date: 1968-11 Impact factor: 6.998

9. The effect of bile salts on the binding of bilirubin by plasma proteins.

Authors: M Fulop; J Sandson
Journal: Clin Sci Date: 1967-12 Impact factor: 6.124

10. The mechanism of bilirubin toxicity studied with purified respiratory enzyme and tissue culture systems.

Authors: M L Cowger; R P Igo; R F Labbe
Journal: Biochemistry Date: 1965-12 Impact factor: 3.162

15 in total

1. Renal failure in obstructive jaundice--clinical aspects.

Authors: J L Dawson
Journal: Postgrad Med J Date: 1975-08 Impact factor: 2.401

2. Renal failure in obstructive jaundice--pathogenic factors.

Authors: E N Wardle
Journal: Postgrad Med J Date: 1975-08 Impact factor: 2.401

3. Consequences of acute renal failure relevant to hepatic failure.

Authors: M J Weston; S P Wilkinson
Journal: Postgrad Med J Date: 1975-08 Impact factor: 2.401

4. Cholangitis with acute renal failure: priorities in therapeutics.

Authors: H Bismuth; H Kuntziger; M B Corlette
Journal: Ann Surg Date: 1975-06 Impact factor: 12.969

5. Ultrastructural changes in the isolated rat kidney induced by conjugated bilirubin and bile acids.

Authors: J L Gollan; B H Billing; S N Huang
Journal: Br J Exp Pathol Date: 1976-10

6. Evaluating role of oxidative stress in determining the pathogenesis of falciparum malaria induced acute renal failure.

Authors: Rachita Nanda; Pramila K Mishra; U K Das; S B Rout; P C Mohapatra; A Panda
Journal: Indian J Clin Biochem Date: 2004-01