Literature DB >> 5780196

Serum kynurenine in rheumatoid arthritis.

H Spiera, R Vallarino.   

Abstract

The concentration of kynurenine has been measured in the serum of patients with rheumatoid arthritis and in a control group. The mean serum concentration was 2.27 +/- 0.688 mug/ml for patients with rheumatoid arthritis and 2.95 +/- 0.825 mug/ml for the control group.KYNURENINE: creatinine clearance ratios were higher in the rheumatoid arthritis than in the control group. These data suggest that the increased urinary excretion of kynurenine by patients with rheumatoid arthritis is due at least in part to renal factors.

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Year:  1969        PMID： 5780196      PMCID： PMC322293          DOI： 10.1172/JCI106043

Source DB:  PubMed          Journal:  J Clin Invest        ISSN： 0021-9738            Impact factor:   14.808


  11 in total

1.  EXCRETION OF TRYPTOPHAN METABOLITES BY PATIENTS WITH RHEUMATOID ARTHRITIS.

Authors:  J H FLINN; J M PRICE; N YESS; R R BROWN
Journal:  Arthritis Rheum       Date:  1964-06

2.  SOME FACTORS INFLUENCING URINARY EXCRETION OF 3-HYDROXYANTHRANILIC ACID.

Authors:  H SPIERA; C L CHRISTIAN
Journal:  Proc Soc Exp Biol Med       Date:  1964 Aug-Sep

3.  TRYPTOPHAN METABOLISM IN RHEUMATIC DISEASE.

Authors:  R S PINALS
Journal:  Arthritis Rheum       Date:  1964-12

Review 4.  ASPECTS OF DISORDERS OF THE KYNURENINE PATHWAY OF TRYPTOPHAN METABOLISM IN MAN.

Authors:  L MUSAJO; C A BENASSI
Journal:  Adv Clin Chem       Date:  1964       Impact factor: 5.394

5.  Metabolism of tryptophan in rheumatoid arthritis.

Authors:  I M BETT
Journal:  Ann Rheum Dis       Date:  1962-03       Impact factor: 19.103

6.  1958 Revision of diagnostic criteria for rheumatoid arthritis.

Authors:  M W ROPES; G A BENNETT; S COBB; R JACOX; R A JESSAR
Journal:  Bull Rheum Dis       Date:  1958-12

7.  The determination in urine of some metabolites of tryptophankynurenine, anthranilic acid and 3-hydroxyanthranilic acid- and reference to the presence of o-aminophenol in urine.

Authors:  S L TOMPSETT
Journal:  Clin Chim Acta       Date:  1959-05       Impact factor: 3.786

8.  Quantitative determination of tryptophan metabolites (via kynurenine) in biologic fluids.

Authors:  D COPPINI; C A BENASSI; M MONTORSI
Journal:  Clin Chem       Date:  1959-10       Impact factor: 8.327

9.  THE IDENTIFICATION OF A FLUORESCENT REDUCING SUBSTANCE IN THE URINE OF PATIENTS WITH RHEUMATOID ARTHRITIS: THE EXCRETION OF 3-HYDROXYANTHRANILIC ACID IN THIS AND OTHER CONDITIONS.

Authors:  M McMillan
Journal:  J Clin Pathol       Date:  1960-03       Impact factor: 3.411

10.  Correlation of kynurenine excretion with liver tryptophan pyrrolase levels in disease and after hydrocortisone induction.

Authors:  K Altman; O Greengard
Journal:  J Clin Invest       Date:  1966-10       Impact factor: 14.808
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  7 in total

Review 1.  Aspects of tryptophan metabolism in health and disease: a review.

Authors:  D P Rose
Journal:  J Clin Pathol       Date:  1972-01       Impact factor: 3.411

2.  IDO2 is a critical mediator of autoantibody production and inflammatory pathogenesis in a mouse model of autoimmune arthritis.

Authors:  Lauren M F Merlo; Elizabeth Pigott; James B DuHadaway; Samantha Grabler; Richard Metz; George C Prendergast; Laura Mandik-Nayak
Journal:  J Immunol       Date:  2014-01-31       Impact factor: 5.422

3.  Tryptophan degradation and neopterin levels in treated rheumatoid arthritis patients.

Authors:  Yesim Ozkan; Guray Mete; Aylin Sepici-Dincel; Vesile Sepici; Bolkan Simsek
Journal:  Clin Rheumatol       Date:  2011-05-10       Impact factor: 2.980

4.  Aspirin effect on cataract formation in patients with rheumatoid arthritis alone or combined with diabetes.

Authors:  E Cotlier
Journal:  Int Ophthalmol       Date:  1981-05       Impact factor: 2.031

5.  Tryptophan metabolism in the isolated perfused liver of the rat: effects of tryptophan concentration, hydrocortisone and allopurinol on tryptophan pyrrolase activity and kynurenine formation.

Authors:  A R Green; H F Woods; M H Joseph
Journal:  Br J Pharmacol       Date:  1976-05       Impact factor: 8.739

Review 6.  IDO2: A Pathogenic Mediator of Inflammatory Autoimmunity.

Authors:  Lauren M F Merlo; Laura Mandik-Nayak
Journal:  Clin Med Insights Pathol       Date:  2016-11-21

Review 7.  Kynurenine Pathway Metabolites as Biomarkers for Amyotrophic Lateral Sclerosis.

Authors:  Vanessa X Tan; Gilles J Guillemin
Journal:  Front Neurosci       Date:  2019-09-20       Impact factor: 4.677
  7 in total

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