Literature DB >> 577687

[Teratologic-neurotoxicologic studies on biglumide (K-2004) and thalidomide].

W Jurecka, H Lassmann, L Stockinger.   

Abstract

Comparison of the teratogenic and neurotoxic influence of thalidomide with the new hypnosedative preparation Biglumide (K-2004) revealed significant differences. Malformations could be seen only after treatment with thalidomide. Some results concerning the thalidomide-treated group of animals could be interpreted as a retardation of development in the posterior root ganglia.

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Year:  1977        PMID： 577687     DOI： 10.1007/bf00293868

Source DB:  PubMed          Journal:  Arch Toxicol        ISSN： 0340-5761            Impact factor:   5.153


  8 in total

1.  [Clinical and electroencephalographic studies with a new hypnosedative K-2004].

Authors:  G Argyropoulos; G Lanner; E Pasquali
Journal:  Wien Med Wochenschr       Date:  1976-02-06

2.  Teratology study of two isoglutamine derivatives.

Authors:  H Koch; F Köhler
Journal:  Arch Toxicol       Date:  1976-01-30       Impact factor: 5.153

3.  [Teratologic study of a new, structurally related to thalidomide, sedative-hypnotic effective compound (K-2004)].

Authors:  L Stockinger; H Koch
Journal:  Arzneimittelforschung       Date:  1969-02

4.  Fetal nerve cell degeneration produced by thalidomide in rabbits.

Authors:  W G McBride
Journal:  Teratology       Date:  1974-12

5.  [Teratological study on the thalidomide-like compounds K-2004 and K-2604 in the mouse and rat].

Authors:  F Köhler; H Koch
Journal:  Arzneimittelforschung       Date:  1974-10

6.  [Toxic injuries in thalidomide medication].

Authors:  E Gibbels
Journal:  Fortschr Neurol Psychiatr Grenzgeb       Date:  1967-08

7.  [Light and electron microscopic studies of late stages of thalidomide polyneuropathy].

Authors:  W Krücke; H H von Hartrott; J M Schröder; E Thomas; E Gibbels; W Scheid
Journal:  Fortschr Neurol Psychiatr Grenzgeb       Date:  1971-01

8.  [Experimental animal studies on the question of thalidomide and nerve damage].

Authors:  M Staemmler; F Lagler
Journal:  Arzneimittelforschung       Date:  1965-05
  8 in total

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