Literature DB >> 5776013

The hepatotoxicity of 1,3-bis (2-chloroethyl)-1-nitrosurea (BCNU) in rats.

G R Thompson, R E Larson.   

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Year:  1969        PMID： 5776013

Source DB:  PubMed          Journal:  J Pharmacol Exp Ther        ISSN： 0022-3565            Impact factor:   4.030


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  7 in total

1.  Distribution of Bratton-Marshall-positive material in mice following intravenous injections of nitrosoureas.

Authors:  P Kari; W R McConnell; J M Finkel; D L Hill
Journal:  Cancer Chemother Pharmacol       Date:  1980       Impact factor: 3.333

2.  Intratumoral injection of BCNU in ethanol (DTI-015) results in enhanced delivery to tumor--a pharmacokinetic study.

Authors:  Daniel A Hamstra; Bradford A Moffat; Daniel E Hall; John M Young; Timothy J Desmond; Julie Carter; Dennis Pietronigro; Kirk A Frey; Alnawaz Rehemtulla; Brian D Ross
Journal:  J Neurooncol       Date:  2005-07       Impact factor: 4.130

3.  Studies on the mechanism of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU)-induced hepatotoxicity. II. Biochemical and morphological characterization of the injury and its prevention by phenobarbital.

Authors:  A E Ahmed; M Grissom; R el-Azhary; A Haque; P J Boor; J Costanzi
Journal:  Cancer Chemother Pharmacol       Date:  1987       Impact factor: 3.333

4.  BCNU-induced quantitative and qualitative changes in hepatic cytochrome P-450 can be correlated with cholestasis.

Authors:  J C Stolzenbach; R E Larson
Journal:  Cancer Chemother Pharmacol       Date:  1990       Impact factor: 3.333

5.  Distribution of 13N in rat tissues following intravenous administration of nitroso-labeled BCNU.

Authors:  B R Freed; R L McQuinn; R S Tilbury; G A Digenis
Journal:  Cancer Chemother Pharmacol       Date:  1982-12       Impact factor: 3.333

6.  The hepatotoxicity of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) in rats. Ultrastructural evidence of a delayed microtubular toxicity.

Authors:  T Ducastelle; G Raguenez-Viotte; H Fouin-Fortunet; M Matysiak; J Hemet; J P Fillastre
Journal:  Cancer Chemother Pharmacol       Date:  1988       Impact factor: 3.333

7.  DTI-015 produces cures in T9 gliosarcoma.

Authors:  Dennis Pietronigro; Frank Drnovsky; Humberto Cravioto; Joseph Ransohoff
Journal:  Neoplasia       Date:  2003 Jan-Feb       Impact factor: 5.715
  7 in total

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