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Literature DB >> 5774044

The relationship between tremor and change in brain acetylcholine concentration produced by injection of tremorine or oxotremorine in the rat.

Abstract

1. The relationship between tremor and change in brain acetylcholine concentration after the injection of tremorine or oxotremorine has been investigated in rats.2. Tremorine produced a significant increase in whole brain acetylcholine and in tremor 5 min after injection. After this time tremor subsided but brain acetylcholine continued to increase.3. Oxotremorine produced tremor within 30 sec. This became maximal within 5 min of injection and then declined rapidly. The brain acetylcholine concentration showed a significant increase 5 min after injection and continued to increase until 30 min afterwards.

Entities: Chemical Disease Species

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Year: 1969 PMID： 5774044 PMCID： PMC1703230

Source DB: PubMed Journal: Br J Pharmacol ISSN： 0007-1188 Impact factor: 8.739

8 in total

1. TREMORINE AND OXOTREMORINE EFFECTS ON ACETYLCHOLINESTERASE AND CHOLINE ACETYLASE FROM RAT BRAIN.

Authors: B HOLMSTEDT; G LUNDGREN; J SCHUBERTH; A SUNDWALL
Journal: Biochem Pharmacol Date: 1965-02 Impact factor: 5.858

2. The peripheral actions of oxotremorine, a metabolite of tremorine.

Authors: A K CHO; W L HASLETT; D J JENDEN
Journal: J Pharmacol Exp Ther Date: 1962-11 Impact factor: 4.030

3. The identification of an active metabolite of tremorine.

Authors: A K CHO; W L HASLETT; D J JENDEN
Journal: Biochem Biophys Res Commun Date: 1961-07-26 Impact factor: 3.575

4. Evaluation of anti-tremor drugs in tremor-induced rodents.

Authors: H C Yen; C A Day
Journal: Arch Int Pharmacodyn Ther Date: 1965-05

5. Rate of metabolism of tremorine and oxotremorine in rats and mice.

Authors: W Hammer; B Karlén; A Rane; F Sjöqvist
Journal: Life Sci Date: 1968-02-01 Impact factor: 5.037

6. The effect of some drugs on the "free" and "bound" acetylcholine content of rat brain.

Authors: J Crossland; P Slater
Journal: Br J Pharmacol Chemother Date: 1968-05

7. The analysis of drug-induced tremor in mice.

Authors: A AHMED; N R TAYLOR
Journal: Br J Pharmacol Chemother Date: 1959-09

8. TREMORINE: ITS EFFECT ON AMINES OF THE CENTRAL NERVOUS SYSTEM.

Authors: A H FRIEDMAN; R J AYLESWORTH; G FRIEDMAN
Journal: Science Date: 1963-09-20 Impact factor: 47.728

8 in total

9 in total

8. The effects of atropine and dyflos on tremor and increase in whole brain acetylcholine produced by injection of oxotremorine in the rat.

Authors: B Cox; D Potkonjak
Journal: Br J Pharmacol Date: 1969-03 Impact factor: 8.739

9. 1H NMR metabonomics indicates continued metabolic changes and sexual dimorphism post-parasite clearance in self-limiting murine malaria model.

Authors: Arjun Sengupta; Soumita Ghosh; Shobhona Sharma; Haripalsingh M Sonawat
Journal: PLoS One Date: 2013-06-24 Impact factor: 3.240

9 in total

The relationship between tremor and change in brain acetylcholine concentration produced by injection of tremorine or oxotremorine in the rat.

1. TREMORINE AND OXOTREMORINE EFFECTS ON ACETYLCHOLINESTERASE AND CHOLINE ACETYLASE FROM RAT BRAIN.

2. The peripheral actions of oxotremorine, a metabolite of tremorine.

3. The identification of an active metabolite of tremorine.

4. Evaluation of anti-tremor drugs in tremor-induced rodents.

5. Rate of metabolism of tremorine and oxotremorine in rats and mice.

6. The effect of some drugs on the "free" and "bound" acetylcholine content of rat brain.

7. The analysis of drug-induced tremor in mice.

8. TREMORINE: ITS EFFECT ON AMINES OF THE CENTRAL NERVOUS SYSTEM.

1. Endosulfan-induced neurotoxicity in rats and mice.

2. Real-time measurement of the contribution of the muscular activity to the metabolic rate in freely moving rats.

3. Quantification of tremor in rats induced by physostigmine.

4. The protective actions of some anticholinergic drugs in sarin poisoning.

5. Effect of oxotremorine on the acetylcholine content of whole brain and various brain regions in the pigeon.

6. Oxotremorine-induced hypertension in the anaesthetized rat.

7. Effects of drugs on tremor and increase in brain acetylcholine produced by oxotremorine in the rat.

8. The effects of atropine and dyflos on tremor and increase in whole brain acetylcholine produced by injection of oxotremorine in the rat.

9. 1H NMR metabonomics indicates continued metabolic changes and sexual dimorphism post-parasite clearance in self-limiting murine malaria model.