| Literature DB >> 577283 |
T R Kordash, R G Van Dellen, J T McCall.
Abstract
To test the efficacy of using a weight-derived formula to determine aminophylline dosages, 50 patients hospitalized for treatment of severe asthma were given intravenous aminophylline infusions at a rate of 0.9 mg/kg/hr to a maximum dosage of 1,500 mg/24 hr. Serum theophylline determinations done 12 to 96 hours after institution of this therapy showed levels greater than 20 mg/liter in 34% of these patients. Reliance on weight-derived formulas can be dangerous.Entities:
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Year: 1977 PMID： 577283
Source DB: PubMed Journal: JAMA ISSN： 0098-7484 Impact factor: 56.272