Literature DB >> 576856

Bioavailability of two hydrochlorothiazide preparations.

B Beermann, M Groschinsky-Grind, B Lindstrom.   

Abstract

Eight healthy volunteers received hydro-chlorothiazide 75 mg as Dichlotride and Esiderx. Maximal plasma levels were significantly (p less than 0.05) higher after Dichlotride than Esidrex, 512 +- 189 and 376 +- 70ng/ml, respectively. However, the bioavailability of the two brands of hydrochlorothiazide did not differ significantly as judged by comparison of the AUC0 leads to 9h and AUC0 leads to chi, and the urinary recovery of hydrochlorothiazide during 48 hrs.

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Year:  1977        PMID： 576856     DOI： 10.1007/bf00606411

Source DB:  PubMed          Journal:  Eur J Clin Pharmacol        ISSN： 0031-6970            Impact factor:   2.953


  4 in total

1.  The mechanism of action of chlorothiazide.

Authors:  K H BEYER
Journal:  Ann N Y Acad Sci       Date:  1958-02-03       Impact factor: 5.691

2.  Gas chromatographic determination of furosemide in plasma using an extractive alkylation technique and an electron capture detector.

Authors:  B Lindström; M Molander
Journal:  J Chromatogr       Date:  1974-12-04

3.  Effect of dissolution media on disintegration and dissolution of hydrochlorothiazide tablets.

Authors:  A S Alam; E L Parrott
Journal:  J Pharm Sci       Date:  1971-05       Impact factor: 3.534

4.  Absorption, metabolism, and excretion of hydrochlorothiazide.

Authors:  B Beermann; M Groschinsky-Grind; A Rosén
Journal:  Clin Pharmacol Ther       Date:  1976-05       Impact factor: 6.875
  4 in total
  6 in total

Review 1.  Clinical pharmacokinetics of diuretics.

Authors:  B Beermann; M Groschinsky-Grind
Journal:  Clin Pharmacokinet       Date:  1980 May-Jun       Impact factor: 6.447

2.  Pharmacokinetics of hydrochlorothiazide in relation to renal function.

Authors:  C Niemeyer; G Hasenfuss; U Wais; H Knauf; M Schäfer-Korting; E Mutschler
Journal:  Eur J Clin Pharmacol       Date:  1983       Impact factor: 2.953

3.  Enhancement of the gastrointestinal absorption of hydrochlorothiazide by propantheline.

Authors:  B Beermann; M Groschinsky-Grind
Journal:  Eur J Clin Pharmacol       Date:  1978-07-30       Impact factor: 2.953

4.  Malabsorption of hydrochlorothiazide following intestinal shunt surgery.

Authors:  L Backman; B Beerman; M Groschinsky-Grind; D Hallberg
Journal:  Clin Pharmacokinet       Date:  1979 Jan-Feb       Impact factor: 6.447

5.  Apparent dose-dependent absorption of chlorothiazide in dogs.

Authors:  D E Resetarits; T R Bates
Journal:  J Pharmacokinet Biopharm       Date:  1979-10

6.  Bioavailability and disposition of metoprolol and hydrochlorothiazide combined in one tablet and of separate doses of hydrochlorothiazide.

Authors:  L Jordö; G Johnsson; P Lundborg; B A Persson; C G Regärdh; O Rönn
Journal:  Br J Clin Pharmacol       Date:  1979-06       Impact factor: 4.335
  6 in total

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