Literature DB >> 5768363

Cell population kinetics: a modified interpretation of the graph of labeled mitoses.

A I Hamilton.   

Abstract

Graphs of labeled mitoses, derived from autoradiographs of cell populations with (3)H-thymidine, show depressions in the curves at their midpoints. These depressions reflect interruption of DNA synthesis midway through S phase. Such interruptions revealed by the method of labeled mitoses should be considered when determining cell-cycle times.

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Year:  1969        PMID: 5768363     DOI: 10.1126/science.164.3882.952

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  6 in total

1.  Quantitative tritium autoradiography of mammalian chromosomes. II. The kinetics of DNA synthesis in individual chromosomes of Chinese hamster fibroblasts.

Authors:  E Stubblefield; M Gay
Journal:  Chromosoma       Date:  1970       Impact factor: 4.316

2.  Cell renewal of oral mucosal epithelium of the rat.

Authors:  A I Hamilton; H J Blackwood
Journal:  J Anat       Date:  1974-04       Impact factor: 2.610

3.  Replication of euchromatin and heterochromatin in a mealybug.

Authors:  C C Huang
Journal:  Chromosoma       Date:  1971       Impact factor: 4.316

4.  Decrease of DNA synthesis in amniotic fluid cells during the middle part of S-phase revealed by differential chromosome staining after incorporation of BrdU.

Authors:  W Schempp; W Vogel
Journal:  Chromosoma       Date:  1978-06-28       Impact factor: 4.316

5.  Kinetics of DNA replication in the Indian muntjac chromosomes as studied by quantitative autoradiography.

Authors:  S Kimura; K Yamazaki; Y Kato
Journal:  Chromosoma       Date:  1980       Impact factor: 4.316

6.  Difference between diploid and aneuploid Chinese hamster cells in replication at mid-S-phase.

Authors:  W Schempp; W Vogel
Journal:  Chromosoma       Date:  1979-06-21       Impact factor: 4.316

  6 in total

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