Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Dissociation of intrinsic factor from its antibody: application to study of pernicious anaemia gastric juice specimens.

Literature DB >> 5764247

Dissociation of intrinsic factor from its antibody: application to study of pernicious anaemia gastric juice specimens.

Abstract

Intrinsic factor antibody may sometimes be concealed in the gastric secretions of pernicious anaemia subjects, being complexed with residual amounts of intrinsic factor.A method is described for dissociating intrinsic factor from its antibody. Antibody to the vitamin-B(12)-binding site of intrinsic factor was identified in 16 (57%) out of 28 samples of pernicious anaemia gastric juice after dissociation but in only 10 before dissociation. There was no clear relationship between the incidence of antibody in the serum and in the gastric juice of these patients.

Entities: Chemical Disease Gene Species

Mesh：

Substances：

Year: 1969 PMID： 5764247 PMCID： PMC1982550 DOI： 10.1136/bmj.1.5642.468

Source DB: PubMed Journal: Br Med J ISSN： 0007-1447

8 in total

1. Gastric intrinsic factor.

Authors: I Chanarin
Journal: Gut Date: 1968-08 Impact factor: 23.059

2. Placental transfer of gastric antibodies.

Authors: J M Fisher; K B Taylor
Journal: Lancet Date: 1967-04-01 Impact factor: 79.321

3. Intrinsic -factor antibodies in gastric juice of pernicious - anemia patients.

Authors: J M Fisher; C Rees; K B Taylor
Journal: Lancet Date: 1966-07-09 Impact factor: 79.321

4. An in vitro test for the detection of serum antibody to intrinsic factor--vitamin B12 complex.

Authors: E Jacob; R F Schilling
Journal: J Lab Clin Med Date: 1966-03

5. Occurrence in gastric juice of antibody to a complex of intrinsic factor and vitamin B12.

Authors: S G Schade; P Feick; M Muckerheide; R F Schilling
Journal: N Engl J Med Date: 1966-09-08 Impact factor: 91.245

6. Effect of transplacental transfer of antibody to intrinsic factor.

Authors: L S Goldberg; E V Barnett; R Desai
Journal: Pediatrics Date: 1967-11 Impact factor: 7.124

7. A METHOD FOR THE ASSAY OF HUMAN GASTRIC INTRINSIC FACTOR AND FOR THE DETECTION AND TITRATION OF ANTIBODIES AGAINST INTRINSIC FACTOR.

Authors: S ARDEMAN; I CHANARIN
Journal: Lancet Date: 1963-12-28 Impact factor: 79.321

8. Intrinsic factor antibodies and intrinsic factor mediated vitamin B-12 absorption in pernicious anaemia.

Authors: S Ardeman; I Chanarin
Journal: Gut Date: 1965-10 Impact factor: 23.059

8 in total

13 in total

Review 1. Gastritis.

Authors: R G Strickland
Journal: Springer Semin Immunopathol Date: 1990

Dissociation of intrinsic factor from its antibody: application to study of pernicious anaemia gastric juice specimens.

1. Gastric intrinsic factor.

2. Placental transfer of gastric antibodies.

3. Intrinsic -factor antibodies in gastric juice of pernicious - anemia patients.

4. An in vitro test for the detection of serum antibody to intrinsic factor--vitamin B12 complex.

5. Occurrence in gastric juice of antibody to a complex of intrinsic factor and vitamin B12.

6. Effect of transplacental transfer of antibody to intrinsic factor.

7. A METHOD FOR THE ASSAY OF HUMAN GASTRIC INTRINSIC FACTOR AND FOR THE DETECTION AND TITRATION OF ANTIBODIES AGAINST INTRINSIC FACTOR.

8. Intrinsic factor antibodies and intrinsic factor mediated vitamin B-12 absorption in pernicious anaemia.

Review 1. Gastritis.

2. Pernicious anaemia.

Review 3. A reappraisal of the nature and significance of chronic atrophic gastritis.

4. Studies on rabbit secretory and serum antibodies to hog intrinsic factor.

5. Experimental humoral and cellular immunity to hog intrinsic factor.

6. A correlative study of immunological phenomena in pernicious anaemia.

Review 7. Alterations in immunologic mechanisms in diseases of the gastrointestinal tract.

8. Intrinsic factor secretion in the gastric juice in diabetes mellitus.

9. In vitro demonstration of delayed hypersensitivity to gastric antigens in pernicious anemia.

10. Vitamin B 12 binding by intrinsic factor.