Literature DB >> 5762767

Deoxycytidine and radiation response: exceedingly high deoxycytidine aminohydrolase activity in human liver.

B Zícha, L Buric.   

Abstract

The activity of deoxycytidine aminohydrolase in the liver of various species including man was investigated. An enormously high activity was found in human liver. This fact explains the extraordinarily low level of deoxycytidine in human urine in comparison with that of other tested species. The suitability of deoxycitidinuria as a biochemical indicator of postirradiation damage in man remains, therefore, an open question.

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Year:  1969        PMID: 5762767     DOI: 10.1126/science.163.3863.191

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  3 in total

1.  Excretion of thymidine and deoxyuridine by irradiated hamsters after administration of exogenous DNA.

Authors:  V F Mikhailov
Journal:  Bull Exp Biol Med       Date:  1974-12       Impact factor: 0.804

Review 2.  Clinical pharmacokinetics of 2'-deoxy-2'-methylidenecytidine (DMDC), a deoxycytidine analogue antineoplastic agent.

Authors:  C J Brindley; R Morrison; R J Gordon; A J Devlin; A van der Gaast; L Verweij; T Funaki
Journal:  Clin Pharmacokinet       Date:  2000-06       Impact factor: 6.447

3.  Nucleoside deaminase: an enzymatic marker for stress erythropoiesis in the mouse.

Authors:  I K Rothman; E D Zanjani; A S Gordon; R Silber
Journal:  J Clin Invest       Date:  1970-11       Impact factor: 14.808

  3 in total

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