Literature DB >> 5762397

Secretory activity and oncogenicity of a cell line (MDCK) derived from canine kidney.

J Leighton, Z Brada, L W Estes, G Justh.   

Abstract

A cell line (MDCK) of dog kidney origin grows on a glass surface as a mosaic of epithelium with many multicellular hemispherical vesicles. The cells lining the blisters actively secrete into the cyst cavities. Suspensions of these cells injected intravenously in the chick embryo produce brain metastases resembling adenocarcinoma.

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Year:  1969        PMID: 5762397     DOI: 10.1126/science.163.3866.472

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  73 in total

1.  Growth of sebaceous cells in monolayer culture.

Authors:  S J Laurent; M I Mednieks; R L Rosenfield
Journal:  In Vitro Cell Dev Biol       Date:  1992-02

Review 2.  Serum-free culture of carcinoma cell lines.

Authors:  P Collodi; C Rawson; D Barnes
Journal:  Cytotechnology       Date:  1991-01       Impact factor: 2.058

Review 3.  Structural biology of epithelial tissue in histophysiologic gradient culture.

Authors:  J Leighton
Journal:  In Vitro Cell Dev Biol       Date:  1992 Jul-Aug

4.  Epithelial cells in culture as a model for the intestinal transport of antimicrobial agents.

Authors:  G Ranaldi; K Islam; Y Sambuy
Journal:  Antimicrob Agents Chemother       Date:  1992-07       Impact factor: 5.191

Review 5.  Kidney epithelial cells release growth factors in response to extracellular signals.

Authors:  F G Toback; M M Walsh-Reitz; S R Mendley; S Kartha
Journal:  Pediatr Nephrol       Date:  1990-07       Impact factor: 3.714

6.  Properties of Wilms' tumor line (TuWi) and pig kidney line (LLC-PK1) typical of normal kidney tubular epithelium.

Authors:  A Perantoni; J J Berman
Journal:  In Vitro       Date:  1979-06

7.  Inducers of mammalian cell differentiation stimulate dome formation in a differentiated kidney epithelial cell line (MDCK).

Authors:  J E Lever
Journal:  Proc Natl Acad Sci U S A       Date:  1979-03       Impact factor: 11.205

8.  Transepithelial transport in cell culture.

Authors:  D S Misfeldt; S T Hamamoto; D R Pitelka
Journal:  Proc Natl Acad Sci U S A       Date:  1976-04       Impact factor: 11.205

9.  Attachment of Cryptosporidium parvum sporozoites to MDCK cells in vitro.

Authors:  D H Hamer; H Ward; S Tzipori; M E Pereira; J P Alroy; G T Keusch
Journal:  Infect Immun       Date:  1994-06       Impact factor: 3.441

10.  Transepithelial transport in cell culture: D-glucose transport by a pig kidney cell line (LLC-PK1).

Authors:  D S Misfeldt; M J Sanders
Journal:  J Membr Biol       Date:  1981-03-15       Impact factor: 1.843

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