Literature DB >> 5762040

Some effects of PCO2 and pH on nerve tissue.

F R Ellis.   

Abstract

1. Rat phrenic nerve preparations were used in vitro to study action potential amplitude and nerve conduction time under varying conditions of Pco(2) and sodium bicarbonate concentration in the surrounding Krebs solution.2. A correlation was found between action potential amplitude and pH but not between action potential amplitude and Pco(2).3. A better correlation was found between conduction time and pH than between conduction time and Pco(2).

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Year:  1969        PMID: 5762040      PMCID: PMC1703090          DOI: 10.1111/j.1476-5381.1969.tb07980.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN: 0007-1188            Impact factor:   8.739


  2 in total

1.  The stabilizing action of carbon dioxide on peripheral nerve fibers and on the neurons of the medullary reticular formation in the rat.

Authors:  F G CARPENTER
Journal:  Ann N Y Acad Sci       Date:  1963-06-24       Impact factor: 5.691

Review 2.  PHYSIOLOGICAL MECHANISMS OF PERIPHERAL NERVE BLOCK BY LOCAL ANESTHETICS.

Authors:  R H DEJONG; I H WAGMAN
Journal:  Anesthesiology       Date:  1963 Sep-Oct       Impact factor: 7.892

  2 in total

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