Literature DB >> 5761893

Effect of salbutamol on spirometry and blood-gas tensions in bronchial asthma.

K N Palmer, M L Diament.   

Abstract

A new bronchodilator drug, salbutamol, reduced airway obstruction in 37 patients with bronchial asthma but did not lead to a significant fall in lowered arterial oxygen tension. This drug, unlike other bronchodilators, appears to have little or no effect on the cardiovascular system, and it is suggested that it does not therefore lead to an intensification of the ventilation/perfusion disturbance in the lung leading to a worsening of hypoxaemia.

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Year:  1969        PMID: 5761893      PMCID: PMC1981823          DOI: 10.1136/bmj.1.5635.31

Source DB:  PubMed          Journal:  Br Med J        ISSN: 0007-1447


  7 in total

1.  Effects of sympathomimetic drugs on pulmonary circulation: with special reference to a new pulmonary vasodilator.

Authors:  D M AVIADO; C F SCHMIDT
Journal:  J Pharmacol Exp Ther       Date:  1957-08       Impact factor: 4.030

2.  Effect of aerosol isoprenaline on blood-gas tensions in severe bronchial asthma.

Authors:  K N Palmer; M L Diament
Journal:  Lancet       Date:  1967-12-09       Impact factor: 79.321

3.  Bronchodilators, blood-gas tensions, and spirometry.

Authors:  K N Palmer; M L Diament
Journal:  Lancet       Date:  1968-06-22       Impact factor: 79.321

4.  Observations on recent increase in mortality from asthma.

Authors:  F E Speizer; R Doll; P Heaf
Journal:  Br Med J       Date:  1968-02-10

5.  Alpha-[(t-Butylamino)methyl]-4-hydroxy-m-xylene-alpha 1,alpha 3-diol (AH.3365): a selective beta-adrenergic stimulant.

Authors:  R T Brittain; J B Farmer; D Jack; L E Martin; W T Simpson
Journal:  Nature       Date:  1968-08-24       Impact factor: 49.962

6.  The effects of posture, oxygen, isoproterenol and atropine on ventilation-perfusion relationships in the lung in asthma.

Authors:  G B Field
Journal:  Clin Sci       Date:  1967-04       Impact factor: 6.124

7.  An effect of isoproterenol on ventilation-perfusion in asthmatic versus normal subjects.

Authors:  R J Knudson; H P Constantine
Journal:  J Appl Physiol       Date:  1967-03       Impact factor: 3.531

  7 in total
  14 in total

Review 1.  Oxygen treatment for acute severe asthma.

Authors:  D Inwald; M Roland; L Kuitert; S A McKenzie; A Petros
Journal:  BMJ       Date:  2001-07-14

2.  Alterations in gas exchange after aerolized orciprenaline in relation to obstruction and hypoxemia.

Authors:  R Thoma; G Siemon; R Keller
Journal:  Pneumonologie       Date:  1975-09-26

3.  Salbutamol--an effective bronchodilator.

Authors:  M Schonell; M Chan-Yeung; L McLean
Journal:  Can Med Assoc J       Date:  1972-02-19       Impact factor: 8.262

4.  Effects of a new stimulator of beta-receptors, terbutaline, on ventilatory capacity, lung resistance, heart rate and blood pressure.

Authors:  B Elgefors; L Wilhelmsen
Journal:  Eur J Clin Pharmacol       Date:  1971-09       Impact factor: 2.953

5.  Evaluation of the effects of isoprenaline and salbutamol aerosols on airways obstruction and pulse rates of children with asthma.

Authors:  G Hambleton; E A Shinebourne
Journal:  Arch Dis Child       Date:  1970-12       Impact factor: 3.791

6.  Comparison of cardiorespiratory effects of isoprenaline and salbutamol in patients with bronchial asthma.

Authors:  D A Warrell; D G Robertson; J N Howes; M E Conolly; J W Paterson; L J Beilin; C T Dollery
Journal:  Br Med J       Date:  1970-01-10

7.  Progress in asthma.

Authors:  K N Palmer
Journal:  Postgrad Med J       Date:  1969-05       Impact factor: 2.401

8.  The effect of intramuscular salbutamol in asthmatics.

Authors:  J Ingram; J Gaddie; C Skinner; K N Palmer
Journal:  Br J Clin Pharmacol       Date:  1975-06       Impact factor: 4.335

9.  Effects of salbutamol and isoprenaline-phenylephrine in reversible airways obstruction.

Authors:  R J Alliott; B D Lang; D R Rawson; W J Leckie
Journal:  Br Med J       Date:  1972-02-26

10.  The presence of -adrenoceptors in the guinea-pig seminal vesicle.

Authors:  M Spedding; D F Weetman
Journal:  Br J Pharmacol       Date:  1972-05       Impact factor: 8.739

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