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Literature DB >> 5748939

Activation of Hageman factor by L-homocystine.

Abstract

L-Homocystine activates Hageman factor, as demonstrated by its capacity to initiate clotting and to induce the evolution of plasma kinins. Perhaps, strategically located deposits of this amino acid are responsible for the unusual frequency of thrombosis in patients with homocystinuria.

Entities: Chemical Disease Species

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Year: 1968 PMID： 5748939 DOI： 10.1126/science.162.3857.1007-a

Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728

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Cited

14 in total

1. Hyperhomocysteinemia in patients with Behçet's disease: is it due to inflammation or therapy?

Authors: Zeki Yesilova; Salih Pay; Cagatay Oktenli; Ugur Musabak; Kenan Saglam; S Yavuz Sanisoglu; Kemal Dagalp; M Kemal Erbil; Ismail H Kocar
Journal: Rheumatol Int Date: 2004-04-01 Impact factor: 2.631

2. The prevalence of homocysteinemia and hypercholesterolemia in angiographically defined coronary heart disease.

Authors: J B Ubbink; W J Vermaak; J M Bennett; P J Becker; D A van Staden; S Bissbort
Journal: Klin Wochenschr Date: 1991-08-16

Review 3. Synergy of homocysteine, microRNA, and epigenetics: a novel therapeutic approach for stroke.

Authors: Anuradha Kalani; Pradeep K Kamat; Suresh C Tyagi; Neetu Tyagi
Journal: Mol Neurobiol Date: 2013-02-22 Impact factor: 5.590

4. Interaction of CA repeat polymorphism of the endothelial nitric oxide synthase and hyperhomocysteinemia in acute coronary syndromes: evidence of gender-specific differences.

Authors: Michael Laule; Christian Meisel; Ines Prauka; Ingolf Cascorbi; Uwe Malzahn; Stephan B Felix; Gert Baumann; Ivar Roots; Karl Stangl; Verena Stangl
Journal: J Mol Med (Berl) Date: 2003-04-02 Impact factor: 4.599

5. On the endogenous mechanism of kinin release. I. Attempts at discriminating kallikreins.

Authors: R Jahrreiss; E Habermann
Journal: Naunyn Schmiedebergs Arch Pharmakol Date: 1971

6. Studies on a complex mechanism for the activation of plasminogen by kaolin and by chloroform: the participation of Hageman factor and additional cofactors.

Authors: D Ogston; C M Ogston; O D Ratnoff; C D Forbes
Journal: J Clin Invest Date: 1969-10 Impact factor: 14.808

Activation of Hageman factor by L-homocystine.

1. Hyperhomocysteinemia in patients with Behçet's disease: is it due to inflammation or therapy?

2. The prevalence of homocysteinemia and hypercholesterolemia in angiographically defined coronary heart disease.

Review 3. Synergy of homocysteine, microRNA, and epigenetics: a novel therapeutic approach for stroke.

4. Interaction of CA repeat polymorphism of the endothelial nitric oxide synthase and hyperhomocysteinemia in acute coronary syndromes: evidence of gender-specific differences.

5. On the endogenous mechanism of kinin release. I. Attempts at discriminating kallikreins.

6. Studies on a complex mechanism for the activation of plasminogen by kaolin and by chloroform: the participation of Hageman factor and additional cofactors.

7. Homocystinuria.

Review 8. Epidemiology of venous thromboembolism.

Review 9. Homocysteine, MTHFR gene polymorphisms, and cardio-cerebrovascular risk.

Review 10. The association of homocysteine and coronary artery disease.