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Literature DB >> 5748583

Medullary carcinoma and thyrocalcitonin.

M Tubiana, G Milhaud, G Coutris, J Lacour, C Parmentier, B Bok.

Abstract

Seven patients with medullary carcinoma of the thyroid were investigated, and the thyrocalcitonin activity of the primary tumours, metastatic deposits, and the serum was estimated.Medullary carcinomas of the thyroid with amyloid stroma contain 100 to 600 times more thyrocalcitonin than normal thyroid tissue, and lymph nodes with metastatic deposits are equally rich in the hormone. High values of thyrocalcitonin are also found in the blood of these patients. Medullary carcinoma of the thyroid with amyloid stroma is the first disease to be recognized in which there is hypersecretion of thyrocalcitonin.

Entities: Disease Species

Mesh：

Substances：

Year: 1968 PMID： 5748583 PMCID： PMC1912102 DOI： 10.1136/bmj.4.5623.87

Source DB: PubMed Journal: Br Med J ISSN： 0007-1447

10 in total

1. EXTRACTION AND PURIFICATION OF CALCITONIN.

Authors: A BAGHDIANTZ; G V FOSTER; A EDWARDS; M A KUMAR; E SLACK; H A SOLIMAN; I MACINTYRE
Journal: Nature Date: 1964-09-05 Impact factor: 49.962

2. Medullary (solid) carcinoma of the thyroid; a clinicopathologic entity.

Authors: J B HAZARD; W A HAWK; G CRILE
Journal: J Clin Endocrinol Metab Date: 1959-01 Impact factor: 5.958

3. Prostaglandin secretion by medullary carcinoma of the thyroid. A possible cause of the associated idarrhoea.

Authors: E D Williams; S M Karim; M Sandler
Journal: Lancet Date: 1968-01-06 Impact factor: 79.321

4. [Epithelioma of the thyroid secreting thyrocalcitonin].

Authors: G Milhaud; M Tubiana; C Parmentier; G Coutris
Journal: C R Acad Hebd Seances Acad Sci D Date: 1968-02-05

5. Granules and thyrocalcitonin-like activity in medullary carcinoma of the thyroid gland.

Authors: J S Meyer; W Abdel-Bari
Journal: N Engl J Med Date: 1968-03-07 Impact factor: 91.245

6. [Medullary epithelioma with amyloid stroma of the thyroid gland].

Authors: R Gérard-Marchant
Journal: J Chir (Paris) Date: 1965-10

7. Pseudohypoparathyroidism: assays of parathyroid hormone and thyrocalcitonin.

Authors: A H Tashjian; A G Frantz; J B Lee
Journal: Proc Natl Acad Sci U S A Date: 1966-10 Impact factor: 11.205

8. Medullary carcinoma of the human thyroid gland. Autoradiographic localization of radioiodine.

Authors: O Ljungberg
Journal: Acta Pathol Microbiol Scand Date: 1966

9. Assay of human thyroid glands for thyrocalcitonin activity.

Authors: M A Aliapoulios; E F Voelkel; P L Munson
Journal: J Clin Endocrinol Metab Date: 1966-08 Impact factor: 5.958

10. Pathological and clinical findings in a series of 67 cases of medullary carcinoma of the thyroid.

Authors: E D Williams; C L Brown; I Doniach
Journal: J Clin Pathol Date: 1966-03 Impact factor: 3.411

10 in total

11 in total

1. Chronic diarrhoea--all in the bowel?

Authors: S Gupta; C J Tibbs; M J G Farthing; R C G Pollok
Journal: J R Soc Med Date: 2007-08 Impact factor: 5.344

2. C and APUD cells and endocrine tumours. Pearse's laboratory in the years 1965-1969: a personal recollection.

Authors: Gianni Bussolati
Journal: Endocr Pathol Date: 2014-06 Impact factor: 3.943

Review 3. Catecholamines--a symposium.

Authors:
Journal: Calif Med Date: 1972-09

Medullary carcinoma and thyrocalcitonin.

1. EXTRACTION AND PURIFICATION OF CALCITONIN.

2. Medullary (solid) carcinoma of the thyroid; a clinicopathologic entity.

3. Prostaglandin secretion by medullary carcinoma of the thyroid. A possible cause of the associated idarrhoea.

4. [Epithelioma of the thyroid secreting thyrocalcitonin].

5. Granules and thyrocalcitonin-like activity in medullary carcinoma of the thyroid gland.

6. [Medullary epithelioma with amyloid stroma of the thyroid gland].

7. Pseudohypoparathyroidism: assays of parathyroid hormone and thyrocalcitonin.

8. Medullary carcinoma of the human thyroid gland. Autoradiographic localization of radioiodine.

9. Assay of human thyroid glands for thyrocalcitonin activity.

10. Pathological and clinical findings in a series of 67 cases of medullary carcinoma of the thyroid.

1. Chronic diarrhoea--all in the bowel?

2. C and APUD cells and endocrine tumours. Pearse's laboratory in the years 1965-1969: a personal recollection.

Review 3. Catecholamines--a symposium.

4. [Optical and ultrastructural study of a case of medullary carcinoma of the thyroid].

5. Two cell types in familial medullary thyroid carcinoma. A histochemical study.

6. Intrafollicular amyloid in primary hyperparathyroidism.

7. Pretargeted radioimmunotherapy (pRAIT) in medullary thyroid cancer (MTC).

8. External radiotherapy and radionuclide in the treatment of thyroid cancer.

9. Ultrastructural study of a calcitonin-secreting tumor. Typhology of the tumor cells and origin of amyloid.

10. Pretargeted radioimmunotherapy in the treatment of metastatic medullary thyroid cancer.