Literature DB >> 574735

Pancuronium reduces halothane requirement in man.

A R Forbes, N H Cohen, E I Eger.   

Abstract

We studied the contribution of pancuronium to anesthetic requirement in man by comparing MAC for halothane alone in 18 patients, with that after intravenous administration of pancuronium, 0.1 mg/kg, in 17 patients. In each group, movement was observed in limbs isolated from the circulation by tourniquet. In patients receiving pancuronium, halothane MAC was 0.55%, whereas the control value was 0.73%. Thus pancuronium reduces halothane MAC by 25%.

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Year:  1979        PMID： 574735     DOI： 10.1213/00000539-197911000-00011

Source DB:  PubMed          Journal:  Anesth Analg        ISSN： 0003-2999            Impact factor:   5.108


  14 in total

Review 1.  Drug interactions with neuromuscular blockers.

Authors:  S Feldman; L Karalliedde
Journal:  Drug Saf       Date:  1996-10       Impact factor: 5.606

2.  Clinical, electrical and mechanical correlations during recovery from neuromuscular blockade with vecuronium.

Authors:  J Y Dupuis; R Martin; J P Tétrault
Journal:  Can J Anaesth       Date:  1990-03       Impact factor: 5.063

3.  Spinal direct current stimulation modulates the activity of gracile nucleus and primary somatosensory cortex in anaesthetized rats.

Authors:  J Aguilar; F Pulecchi; R Dilena; A Oliviero; A Priori; G Foffani
Journal:  J Physiol       Date:  2011-08-08       Impact factor: 5.182

Review 4.  Safety considerations in the use of drug combinations during general anaesthesia.

Authors:  E S Ransom; R A Mueller
Journal:  Drug Saf       Date:  1997-02       Impact factor: 5.606

5.  Effect of rocuronium on the bispectral index under anesthesia and tracheal intubation.

Authors:  Hui Yue; Jinyu Han; Ling Liu; Kaiyuan Wang; Jincheng Li
Journal:  Exp Ther Med       Date:  2016-10-20       Impact factor: 2.447

6.  Sugammadex at both high and low doses does not affect the depth of anesthesia or hemodynamics: a randomized double blind trial.

Authors:  Argyro Fassoulaki; Konstantinos Chondrogiannis; Chryssoula Staikou
Journal:  J Clin Monit Comput       Date:  2016-02-19       Impact factor: 2.502

7.  Response of lower esophageal contractility to changing concentrations of halothane or isoflurane: a multicenter study.

Authors:  G A Maccioli; D R Kuni; G Silvay; J M Evans; J M Calkins; J A Kaplan
Journal:  J Clin Monit       Date:  1988-10

8.  Effects of neuromuscular block on systemic and cerebral hemodynamics and bispectral index during moderate or deep sedation in critically ill patients.

Authors:  Satoki Inoue; Masahiko Kawaguchi; Noriyuki Sasaoka; Katsuji Hirai; Hitoshi Furuya
Journal:  Intensive Care Med       Date:  2006-02-01       Impact factor: 17.440

9.  Assessment of immediate post-anaesthetic recovery in young children following intravenous morphine infusions, halothane, and isoflurane.

Authors:  H M Chinyanga; H Vandenberghe; S MacLeod; S Soldin; L Endrenyi
Journal:  Can Anaesth Soc J       Date:  1984-01

10.  Pancuronium, vecuronium, and d-tubocurarine inhibit and succinylcholine stimulates choline acetyltransferase activity.

Authors:  J R Kambam; V E Janson; P Day; B V Sastry
Journal:  Can J Anaesth       Date:  1990-09       Impact factor: 5.063
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