Literature DB >> 574106

[Problems in the genetics of stress. IV. A genetic analysis of the level of autonomic reactivity in emotional stress in rats].

A V Osadchuk, A L Markel', R A Khusainov, E V Naumenko, D K Beliaev.   

Abstract

A genetic analysis of hypertensive reactions under condition of emotional stress in three inbred strains of rats (Wistar, Sprague-Dowly and August) and their F1 reciprocal hybrids is carried out. Highly significant genotypic differences in the arterial pressure level during emotional stress and no genetic diversity in the basal state were found. Application of our own methos to genetic analysis of incomplete diallelic tables for Griffing's experimental design 1 (model 1) showed an existence of significant additive component of genetic variance in autonomic reactivity under the stress. The role of the stress as a factor of differentiation of the genetic structure of population is discussed.

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Year:  1979        PMID: 574106

Source DB:  PubMed          Journal:  Genetika        ISSN: 0016-6758


  2 in total

1.  The region of rat chromosome 10 (the ngfr gene locus) is associated with blood pressure increase in response to emotional stress.

Authors:  O E Redina; N E Lapteva; S L Khanina; N A Machanova; G M Dymshits; A L Markel
Journal:  Dokl Biochem Biophys       Date:  2001 Sep-Oct       Impact factor: 0.788

2.  Stress Reactivity, Susceptibility to Hypertension, and Differential Expression of Genes in Hypertensive Compared to Normotensive Patients.

Authors:  Dmitry Oshchepkov; Irina Chadaeva; Rimma Kozhemyakina; Karina Zolotareva; Bato Khandaev; Ekaterina Sharypova; Petr Ponomarenko; Anton Bogomolov; Natalya V Klimova; Svetlana Shikhevich; Olga Redina; Nataliya G Kolosova; Maria Nazarenko; Nikolay A Kolchanov; Arcady Markel; Mikhail Ponomarenko
Journal:  Int J Mol Sci       Date:  2022-03-04       Impact factor: 5.923

  2 in total

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