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Literature DB >> 573181

Ultrastructural reactions of spinal ganglia to tri-ortho-cresyl-phosphate: effects of neurotoxicity.

Abstract

The ultrastructure of neurons in spinal ganglia of the domestic fowl poisoned with tri-ortho-cresyl-phosphate (TOCP) shows characteristic changes. The light neurons react to TOCP by a marked increase in the number of neurofilaments. These neurons also contain mitochondria in various degenerative stages. Several of the altered mitochondria show an increasing osmiophilia. Some of the darker neurons display a hypertrophy of the endoplasmic reticulum or a relative increase of neurofilaments. The mitochondria in some of these cells show early stages of degeneration. These changes appear 13 days after TOCP ingestion.

Entities: Chemical Disease

Mesh：

Substances：

Year: 1979 PMID： 573181 DOI： 10.1007/bf00236079

Source DB: PubMed Journal: Cell Tissue Res ISSN： 0302-766X Impact factor: 5.249

15 in total

1. INVESTIGATIONS ON THE ULTRASTRUCTURAL CHANGES OF THE SPINAL GANGLION NEURONS IN THE COURSE OF AXON REGENERATION AND CELL HYPERTROPHY. I. CHANGES DURING AXON REGENERATION.

Authors: E PANNESE
Journal: Z Zellforsch Mikrosk Anat Date: 1963-09-03

Review 2. CHEMICALLY (TCP) INDUCED FIBRE DEGENERATION IN THE CENTRAL NERVOUS SYSTEM, WITH REFERENCE TO CLINICAL AND NEUROPHARMACOLOGICAL ASPECTS.

Authors: P GLEES; H JANZIK
Journal: Prog Brain Res Date: 1965 Impact factor: 2.453

9. Synaptic morphology in the spinal cord of normal and tricresylphosphate (TCP) poisoned hen. An electron microscopic study.

Authors: M M Ahmed
Journal: Acta Neuropathol Date: 1971 Impact factor: 17.088

10. Effects of mitotic spindle inhibitors on neurotubules and neurofilaments in anterior horn cells.

Authors: H Wisniewski; M L Shelanski; R D Terry
Journal: J Cell Biol Date: 1968-07 Impact factor: 10.539

2 in total

1. Ultrastructural changes in the autonomic interneuron synapse activated during acetylcholinesterase suppression.

Authors: O S Sotnikov; A A Aliev
Journal: Neurosci Behav Physiol Date: 1988 Mar-Apr

2. Ultrastructural changes in neurons and neuroglia of the avian telencephalon (hyperstriatum accessorium) following tri-ortho-cresyl-phosphate intoxication.

Authors: P E Spoerri; P Glees
Journal: Cell Tissue Res Date: 1980 Impact factor: 5.249

2 in total

Ultrastructural reactions of spinal ganglia to tri-ortho-cresyl-phosphate: effects of neurotoxicity.

1. INVESTIGATIONS ON THE ULTRASTRUCTURAL CHANGES OF THE SPINAL GANGLION NEURONS IN THE COURSE OF AXON REGENERATION AND CELL HYPERTROPHY. I. CHANGES DURING AXON REGENERATION.

Review 2. CHEMICALLY (TCP) INDUCED FIBRE DEGENERATION IN THE CENTRAL NERVOUS SYSTEM, WITH REFERENCE TO CLINICAL AND NEUROPHARMACOLOGICAL ASPECTS.

3. The absorption of tri-ortho-cresyl phosphate through the skin of hens and its neurotoxic effects.

4. Fine structure of neurons in the spinal ganglion of slow loris (Nycticebus coucang coucang).

5. Neuronal aging in cultures. An electron-microscopic study.

6. Mitochondrial variations in the spinal ganglion cells of the slow loris: an electron microscopic study.

7. A note on the neuroglia in normal and tricresylphosphate (TCP) poisoned hen.

8. Mitochondrial degeneration after organic phosphate poisoning in prosimian primates.

9. Synaptic morphology in the spinal cord of normal and tricresylphosphate (TCP) poisoned hen. An electron microscopic study.

10. Effects of mitotic spindle inhibitors on neurotubules and neurofilaments in anterior horn cells.

1. Ultrastructural changes in the autonomic interneuron synapse activated during acetylcholinesterase suppression.

2. Ultrastructural changes in neurons and neuroglia of the avian telencephalon (hyperstriatum accessorium) following tri-ortho-cresyl-phosphate intoxication.