Hypercalciuria relative to total solutes in nephrolithiasis.

Urines obtained from normal controls, from patients with calcium-containing renal stones, and from acutely ill patients suffering from various other renal or electrolyte disorders were analysed for Na, K, NH(4), Ca, Mg, inorganic phosphate and sulphate, pH, and osmolality.The stone-formers' urines were found to be characterized by hypercalciuria relative to Na, K, Mg, SO(4), osmolality, and ionic strength. Hypercalciuria relative to osmolality was a more consistent finding than hypercalciuria relative to Na.These findings are in keeping with the supposition that calcium-containing renal stones occur in urine saturated with calcium salts.