Clotting factor v activity in plasma cryoproteins.

Plasma cryoprecipitates containing considerable quantities of clotting factor V were observed in five patients. The unusual factor V activity was not associated with significant amounts of cryofibrinogen. Clinically, the symptoms were not distinguishable from those of other cryopathies. The abnormality did not lead to a deficiency of factor V in the circulating blood nor to a haemorrhagic diathesis.