Literature DB >> 571138

Carcinogenic effects of Di(2-hydroxypropyl)nitrosamine (DHPN) in male Wistar rats: promotion of pancreatic cancer by a raw soya flour diet.

D A Levison, R G Morgan, J S Brimacombe, D Hopwood, G Coghill, K G Wormsley.   

Abstract

Di(2-hydroxypropyl)nitrosamine was administered to rats fed raw or heated (control) soya flour diets. The group fed raw soya flour developed hyperplastic and adenomatous pancreatic nodules and pancreatic adenocarcinomata. We conclude that a diet of raw soya flour augments the carcinogenicity of pancreatic carcinogens in the rat.

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Year:  1979        PMID： 571138     DOI： 10.3109/00365527909179873

Source DB:  PubMed          Journal:  Scand J Gastroenterol        ISSN： 0036-5521            Impact factor:   2.423


  9 in total

1.  Induction of a mixed ductal-squamous-islet cell carcinoma in a rat treated with a tobacco-specific carcinogen.

Authors:  P M Pour; A Rivenson
Journal:  Am J Pathol       Date:  1989-03       Impact factor: 4.307

2.  Induction of pancreatic tumours by longterm duodenogastric reflux.

Authors:  P R Taylor; R H Dowling; T J Palmer; D C Hanley; G M Murphy; R C Mason; I McColl
Journal:  Gut       Date:  1989-11       Impact factor: 23.059

3.  Structural changes of the exocrine pancreas in a patient with cholecystolithiasis.

Authors:  L Magnani; D Bani; G Biliotti; T Bani Sacchi
Journal:  Int J Pancreatol       Date:  1992-08

4.  Modification of pancreatic carcinogenesis in the hamster model. 2. The effect of partial pancreatectomy.

Authors:  P M Pour; T Donnelly; K Stepan; K Muffly
Journal:  Am J Pathol       Date:  1983-01       Impact factor: 4.307

5.  Longterm pancreaticobiliary diversion stimulates hyperplastic and adenomatous nodules in the rat pancreas: a new model for spontaneous tumour formation.

Authors:  N H Stace; T J Palmer; S Vaja; R H Dowling
Journal:  Gut       Date:  1987       Impact factor: 23.059

6.  Initiation of a transplantable fibrosarcoma by the synergism of two non-initiators, alpha-tocopherol and soya oil.

Authors:  P Constantinides; M Harkey
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1985

7.  Protective effect of Emilia sonchifolia (L.) against high protein diet induced oxidative stress in pancreas of Wistar rats.

Authors:  Dominic Sophia; Paramasivam Ragavendran; Chinthamony Arul Raj; Velliyur Kanniappan Gopalakrishnan
Journal:  J Pharm Bioallied Sci       Date:  2012-01

Review 8.  Effects of soybean flour on the pancreas of rats.

Authors:  E E McGuinness; R G Morgan; K G Wormsley
Journal:  Environ Health Perspect       Date:  1984-06       Impact factor: 9.031

Review 9.  Experimental pancreatic hyperplasia and neoplasia: effects of dietary and surgical manipulation.

Authors:  P Watanapa; R C Williamson
Journal:  Br J Cancer       Date:  1993-05       Impact factor: 7.640
  9 in total

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