Literature DB >> 570071

[Therapy of a refractory idiopathic thrombocytopenic purpura by vinblastine-loaded thrombocytes (author's transl)].

U Budde, R Schmidt, J Gerloff, F Etzel.   

Abstract

A 15-year-old patient with ITP which was refractory to corticosteroids, splenectomy, and immunosuppressive therapy with vincristine was twice treated with platelets loaded with vinblastine. Five days after the application of the platelets vinblastine complex the platelets began to rise up to 600 X 10(9)/l. The remission has lasted until now for more than 15 weeks. The therapy showed no major side effects except for a transient granulocytopenia.

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Year:  1979        PMID: 570071     DOI: 10.1007/bf01007955

Source DB:  PubMed          Journal:  Blut        ISSN: 0006-5242


  4 in total

1.  Vincristine therapy of idiopathic and secondary thrombocytopenias.

Authors:  Y S Ahn; W J Harrington; R C Seelman; C S Eytel
Journal:  N Engl J Med       Date:  1974-08-22       Impact factor: 91.245

2.  Immunosuppressive therapy of chronic idiopathic thrombocytopenic purpura.

Authors:  S C Finch; O Castro; M Cooper; W Covey; R Erichson; P McPhedran
Journal:  Am J Med       Date:  1974-01       Impact factor: 4.965

3.  The treatment of idiopathic thrombocytopenia with vinblastine-loaded platelets.

Authors:  Y S Ahn; J J Byrnes; W J Harrington; M L Cayer; D S Smith; D E Brunskill; L M Pall
Journal:  N Engl J Med       Date:  1978-05-18       Impact factor: 91.245

Review 4.  Treatment of idiopathic thrombocytopenic purpura (ITP).

Authors:  Y S Ahn; W J Harrington
Journal:  Annu Rev Med       Date:  1977       Impact factor: 13.739

  4 in total

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