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Literature DB >> 569973

Aryl hydrocarbon hydroxylase in cultured lymphocytes of twins.

B Paigen, E Ward, K Steenland, L Houten, H L Gurtoo, J Minowada.

Abstract

Measurement of aryl hydrocarbon hydroxylase (AHH) in cultured lymphocytes of 18 monozygotic and 30 dizygotic twin pairs showed that basal and induced AHH activity and AHH inducibility are heritable traits. The data are consistent with AHH inducibility being determined by a single or a very few polymorphic genes.

Entities: Gene

Mesh：

Substances：

Year: 1978 PMID： 569973 PMCID： PMC1685596

Source DB: PubMed Journal: Am J Hum Genet ISSN： 0002-9297 Impact factor: 11.025

24 in total

1. FAMILIAL FACTORS IN HUMAN LUNG CANCER AND SMOKING.

Authors: G K TOKUHATA
Journal: Am J Public Health Nations Health Date: 1964-01

2. Distribution of aryl hydrocarbon hydroxylase inducibility in cultured human lymphocytes.

Authors: B Paigen; J Minowada; H L Gurtoo; K Paigen; N B Parker; E Ward; N T Hayner; I D Bross; F Bock; R Vincent
Journal: Cancer Res Date: 1977-06 Impact factor: 12.701

3. Questionable relation of aryl hydrocarbon hydroxylase to lung-cancer risk.

Authors: B Paigen; H L Gurtoo; J Minowada; L Houten; R Vincent; K Paigen; N B Parker; E Ward; N T Hayner
Journal: N Engl J Med Date: 1977-08-18 Impact factor: 91.245

4. Factors influencing the measurement and the reproducibility of aryl hydrocarbon hydroxylase activity in culutred human lymphocytes.

Authors: H L Gurtoo; J Minowada; B Paigen; N B Parker; N T Hayner
Journal: J Natl Cancer Inst Date: 1977-09 Impact factor: 13.506

5. Evidence for a 2,3-epoxide as an intermediate in the microsomal metabolism of benzo[a]pyrene to 3-hydroxybenzo[a]pyrene.

Authors: S K Yang; P P Roller; P P Fu; R G Harvey; H V Gelboin
Journal: Biochem Biophys Res Commun Date: 1977-08-22 Impact factor: 3.575

6. Interindividual and intraindividual variations in aryl hydrocarbon hydroxylase in monocytes from monozygotic and dizygotic twins.

Authors: T Okuda; E S Vesell; E Plotkin; R Tarone; R C Bast; H V Gelboin
Journal: Cancer Res Date: 1977-11 Impact factor: 12.701

7. Immunochemical evidence for six forms of rat liver cytochrome P450 obtained using antibodies against purified rat liver cytochromes P450 and P448.

Authors: P E Thomas; A Y Lu; D Ryan; S B West; J Kawalek; W Levin
Journal: Mol Pharmacol Date: 1976-09 Impact factor: 4.436

8. Properties of electrophoretically homogeneous phenobarbital-inducible and beta-naphthoflavone-inducible forms of liver microsomal cytochrome P-450.

Authors: D A Haugen; M J Coon
Journal: J Biol Chem Date: 1976-12-25 Impact factor: 5.157

9. (+/-)-trans-7,8-dihydroxy-7,8-dihydrobenzo (a)pyrene: a potent skin carcinogen when applied topically to mice.

Authors: W Levin; A W Wood; H Yagi; D M Jerina; A H Conney
Journal: Proc Natl Acad Sci U S A Date: 1976-11 Impact factor: 11.205

10. Genetic control of interindividual variations in the inducibility of aryl hydrocarbon hydroxylase in cultured human lymphocytes.

Authors: S A Atlas; E S Vesell; D W Nebert
Journal: Cancer Res Date: 1976-12 Impact factor: 12.701

6 in total

4. Aryl hydrocarbon hydroxylase activity in pulmonary alveolar macrophages and lymphocytes from lung cancer and noncancer patients: a correlation with family histories of cancer.

Authors: T L McLemore; R R Martin; R R Springer; N Wray; E T Cantrell; D L Busbee
Journal: Biochem Genet Date: 1979-10 Impact factor: 1.890

Review 5. Methods for analysis of the mutagenicity of indirect mutagens/carcinogens in eukaryotic cells.

Authors: S Madle; G Obe
Journal: Hum Genet Date: 1980 Impact factor: 4.132

Review 6. Genetic differences in susceptibility to chemically induced myelotoxicity and leukemia.

Authors: D W Nebert
Journal: Environ Health Perspect Date: 1981-06 Impact factor: 9.031