Literature DB >> 5699205

Hemin: an inhibitor of erythroid cell ribonuclease.

E R Burka.   

Abstract

Hemin, in concentrations which stimulate protein synthesis and stabilize polyribosomes in reticulocytes, is a potent inhibitor of ribonuclease activity in the erythroid cell. This may offer a partial explanation for the way in which hemin acts to accelerate globin synthesis and thus synchronize the synthesis of hemin and globin in the maturing erythroid cell.

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Year:  1968        PMID： 5699205     DOI： 10.1126/science.162.3859.1287

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  4 in total

1.  RNase activity in erythroid cell lysates.

Authors:  E R Burka
Journal:  J Clin Invest       Date:  1969-09       Impact factor: 14.808

2.  On the nature of sickle-cell disease in the Arabian Peninsula.

Authors:  M A El-Hazmi
Journal:  Hum Genet       Date:  1979       Impact factor: 4.132

3.  Synthesis and turnover of globin mRNA in murine erythroleukemia cells induced with hemin.

Authors:  K Lowenhaupt; J B Lingrel
Journal:  Proc Natl Acad Sci U S A       Date:  1979-10       Impact factor: 11.205

4.  Synthesis of vaccinia viral proteins in cytoplasmic extracts. I. Incorporation of radioactively labeled amino acids into polypeptides.

Authors:  E Katz; B Moss
Journal:  J Virol       Date:  1969-10       Impact factor: 5.103
  4 in total

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