| Literature DB >> 5698838 |
Abstract
Rats show a significant degree of tolerance to a second dose of morphine, with the degree of tolerance increasing the longer the delay between the two doses of morphine. To measure the morphine effect a foot-shock attenuation procedure that allowed the animal to adjust the shock intensity was used in studying delays of up to 180 days.Entities:
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Year: 1968 PMID: 5698838 DOI: 10.1126/science.162.3857.1011
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728