Literature DB >> 5698838

Morphine: single-dose tolerance.

C Kornetsky, G Bain.   

Abstract

Rats show a significant degree of tolerance to a second dose of morphine, with the degree of tolerance increasing the longer the delay between the two doses of morphine. To measure the morphine effect a foot-shock attenuation procedure that allowed the animal to adjust the shock intensity was used in studying delays of up to 180 days.

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Year:  1968        PMID: 5698838     DOI: 10.1126/science.162.3857.1011

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  6 in total

1.  Single-dose tolerance to the behavioral effects of dibutyryl cyclic AMP in mice.

Authors:  M Weiner; J W Olson
Journal:  Psychopharmacology (Berl)       Date:  1977-08-31       Impact factor: 4.530

2.  Infuluence of 6-hydroxydopamine on the effect of morphine on the tail-flick latency.

Authors:  K Nakamura; R Kuntzman; A C Maggio; V Augulis; A H Conney
Journal:  Psychopharmacologia       Date:  1973-07-17

3.  Analgesia and decrement in operant performance in socially defeated mice: selective cross-tolerance to morphine and antagonism by naltrexone.

Authors:  K A Miczek; J T Winslow
Journal:  Psychopharmacology (Berl)       Date:  1987       Impact factor: 4.530

Review 4.  Are astroglial cells involved in morphine tolerance?

Authors:  L Rönnbäck; E Hansson
Journal:  Neurochem Res       Date:  1988-02       Impact factor: 3.996

5.  Angiotensin II receptor type 1 blocker candesartan improves morphine tolerance by reducing morphine‑induced inflammatory response and cellular activation of BV2 cells via the PPARγ/AMPK signaling pathway.

Authors:  Wenxin Zhao; Feiyan Shen; Jixiang Yao; Shanshan Su; Zhongmin Zhao
Journal:  Mol Med Rep       Date:  2022-08-25       Impact factor: 3.423

6.  Morphine induces endocytosis of neuronal mu-opioid receptors through the sustained transfer of Galpha subunits to RGSZ2 proteins.

Authors:  María Rodríguez-Muñoz; Elena de la Torre-Madrid; Pilar Sánchez-Blázquez; Javier Garzón
Journal:  Mol Pain       Date:  2007-07-17       Impact factor: 3.395

  6 in total

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