Literature DB >> 569631

Sexual differentiation of the brain.

R A Gorski.   

Abstract

Ontogenetically the brain is female and, regardless of genetic sex, would remain so if not exposed to gonadal hormones at a critical stage in its development. Research in animals in which this exposure occurs after birth is providing evidence that the differentiation of the neural substrates that regulate pituitary activity and sexual behavior is localized to a particular hypothalamic region.

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Year:  1978        PMID: 569631     DOI: 10.1080/21548331.1978.11707415

Source DB:  PubMed          Journal:  Hosp Pract        ISSN: 0018-5809


  7 in total

1.  Developmental programming: reproductive endocrinopathies in the adult female sheep after prenatal testosterone treatment are reflected in altered ontogeny of GnRH afferents.

Authors:  Heiko T Jansen; John Hershey; Andrea Mytinger; Douglas L Foster; Vasantha Padmanabhan
Journal:  Endocrinology       Date:  2011-09-20       Impact factor: 4.736

Review 2.  Epigenetic effects of endocrine-disrupting chemicals on female reproduction: an ovarian perspective.

Authors:  Aparna Mahakali Zama; Mehmet Uzumcu
Journal:  Front Neuroendocrinol       Date:  2010-07-04       Impact factor: 8.606

3.  Developmental nicotine exposure and masculinization of the rat preoptic area.

Authors:  Rashmi Joglekar; Marty Cauley; Taylor Lipsich; David L Corcoran; Heather B Patisaul; Edward D Levin; Joel N Meyer; Margaret M McCarthy; Susan K Murphy
Journal:  Neurotoxicology       Date:  2022-01-10       Impact factor: 4.294

4.  Effects of perinatal bisphenol A exposure on the volume of sexually-dimorphic nuclei of juvenile rats: A CLARITY-BPA consortium study.

Authors:  Sheryl E Arambula; Joelle Fuchs; Jinyan Cao; Heather B Patisaul
Journal:  Neurotoxicology       Date:  2017-09-07       Impact factor: 4.294

5.  Sexual differentiation of the rodent brain: dogma and beyond.

Authors:  Kathryn M Lenz; Bridget M Nugent; Margaret M McCarthy
Journal:  Front Neurosci       Date:  2012-02-21       Impact factor: 4.677

6.  Distribution of androgen receptor mRNA in the prepubertal male and female mouse brain.

Authors:  Alexandra L Cara; Emily L Henson; Bethany G Beekly; Carol F Elias
Journal:  J Neuroendocrinol       Date:  2021-12-05       Impact factor: 3.870

7.  Developmental exposure to Ethinylestradiol affects transgenerationally sexual behavior and neuroendocrine networks in male mice.

Authors:  Lyes Derouiche; Matthieu Keller; Anne Hélène Duittoz; Delphine Pillon
Journal:  Sci Rep       Date:  2015-12-07       Impact factor: 4.379

  7 in total

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