Literature DB >> 56926

Metabolic products of microorganisms. 155. Modes of action of rinamycin and derinamycin.

K Uchida, H Zähner.   

Abstract

Rinamycin interfered with DNA-polymerase I of Escherichia coli in cell-free systems more effectively than actinomycin C. Its inhibitory action could be relieved by increasing the concentration of polymerase. The rinamycin concentrations that caused effective inhibition of the RNA-polymerase reaction in vitro were approximately 10 times higher than those required to inhibit the DNA-polymerase reaction in vitro.

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Year:  1976        PMID： 56926     DOI： 10.1007/bf00446835

Source DB:  PubMed          Journal:  Arch Microbiol        ISSN： 0302-8933            Impact factor:   2.552


  14 in total

1.  ANTIMETABOLITES AFFECTING PROTEIN OR NUCLEIC ACID SYNTHESIS. PHLEOMYCIN, AN INHIBITOR OF DNA POLYMERASE.

Authors:  A FALASCHI; A KORNBERG
Journal:  Fed Proc       Date:  1964 Sep-Oct

2.  The role of deoxyribonucleic acid in ribonucleic acid synthesis. III. The inhibition of the enzymatic synthesis of ribonucleic acid and deoxyribonucleic acid by actinomycin D and proflavin.

Authors:  J HURWITZ; J J FURTH; M MALAMY; M ALEXANDER
Journal:  Proc Natl Acad Sci U S A       Date:  1962-07-15       Impact factor: 11.205

3.  Influence of netropsin and distamycin A on the secondary structure and template activity of DNA.

Authors:  C Zimmer; B Puschendorf; H Grunicke; P Chandra; H Venner
Journal:  Eur J Biochem       Date:  1971-07-29

4.  Interaction of kanchanomycin with nucleic acids. 3. Contrasts in the mechanisms of inhibition of ribonucleic acid and deoxyribonucleic acid polymerase reactions.

Authors:  P B Joel; P A Friedman; I H Goldberg
Journal:  Biochemistry       Date:  1970-10-27       Impact factor: 3.162

5.  Mechanism of action of chromomycin A3. 3. On the binding of chromomycin A3 with DNA and physiochemical properties of the complex.

Authors:  M Kamiyama
Journal:  J Biochem       Date:  1968-05       Impact factor: 3.387

6.  Interaction of kanchanomycin with nucleic acids. I. Physical properties of the complex.

Authors:  P A Friedman; P B Joel; I H Goldberg
Journal:  Biochemistry       Date:  1969-04       Impact factor: 3.162

7.  Inhibition of RNA and DNA polymerase reactions by pluramycin A.

Authors:  N Tanaka; K Nagai; H Yamaguchi; H Umezawa
Journal:  Biochem Biophys Res Commun       Date:  1965-11-22       Impact factor: 3.575

8.  The inhibition of RNA and DNA polymerases by hedamycin.

Authors:  P B Joel; I H Goldberg
Journal:  Biochim Biophys Acta       Date:  1970-12-14

9.  Physicochemical properties of complexes between deoxyribonucleic acid and antibiotics which affect ribonucleic acid synthesis (actinomycin, daunomycin, cinerubin, nogalamycin, chormomycin, mithramycin, and olivomycin).

Authors:  W Kersten; H Kersten; W Szybalski
Journal:  Biochemistry       Date:  1966-01       Impact factor: 3.162

10.  Letter: Biological effects of azomycin (2-nitro-imidazole): inhibition of ribonucleotide reductase.

Authors:  T Saeki; H Umezawa; T Tokieda-Fujishige; M Hori
Journal:  J Antibiot (Tokyo)       Date:  1974-03       Impact factor: 2.649
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