Literature DB >> 5690956

Potential antileukemic and immunosuppressive drugs. Preparation and in vitro pharmacological acitivity of some benzo-2,1,3-oxadiazoles (benzofurazans) and their N-oxides (benzofuroxans).

P B Ghosh, M W Whitehouse.   

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Year:  1968        PMID: 5690956     DOI: 10.1021/jm00308a027

Source DB:  PubMed          Journal:  J Med Chem        ISSN: 0022-2623            Impact factor:   7.446


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  12 in total

1.  7-Nitro-4-(phenylthio)benzofurazan is a potent generator of superoxide and hydrogen peroxide.

Authors:  Eric V Patridge; Emma S E Eriksson; Philip G Penketh; Raymond P Baumann; Rui Zhu; Krishnamurthy Shyam; Leif A Eriksson; Alan C Sartorelli
Journal:  Arch Toxicol       Date:  2012-06-06       Impact factor: 5.153

2.  Furoxans (1,2,5-oxadiazole-N-oxides) as novel NO mimetic neuroprotective and procognitive agents.

Authors:  Isaac T Schiefer; Lawren VandeVrede; Mauro Fa'; Ottavio Arancio; Gregory R J Thatcher
Journal:  J Med Chem       Date:  2012-03-30       Impact factor: 7.446

3.  7-chloro-4-nitrobenzo-2-oxa-1,3-diazole: a new fluorigenic reagent for amino acids and other amines.

Authors:  P B Ghosh; M W Whitehouse
Journal:  Biochem J       Date:  1968-06       Impact factor: 3.857

4.  Identification, synthesis and evaluation of substituted benzofurazans as inhibitors of CREB-mediated gene transcription.

Authors:  Fuchun Xie; Bingbing X Li; Candice Broussard; Xiangshu Xiao
Journal:  Bioorg Med Chem Lett       Date:  2013-07-31       Impact factor: 2.823

5.  4-Chloro-7-nitrobenzo-2-oxa-1,3-diazole as a reactivity probe for the investigation of the thiol proteinases. evidence that ficin and bromelain may lack carboxyl groups conformationally equivalent to that of aspartic acid-158 of papain.

Authors:  M Shipton; T Stuchbury; K Brocklehurst
Journal:  Biochem J       Date:  1976-11       Impact factor: 3.857

6.  Ionization characteristics and chemical influences of aspartic acid residue 158 of papain and caricain determined by structure-related kinetic and computational techniques: multiple electrostatic modulators of active-centre chemistry.

Authors:  M A Noble; S Gul; C S Verma; K Brocklehurst
Journal:  Biochem J       Date:  2000-11-01       Impact factor: 3.857

7.  Impairment of the catalytic activity of Escherichia coli ribonucleic acid polymerase by a unique reaction of 4-chloro-7-nitrobenzofurazan.

Authors:  S C Bratcher; K Nitta; M J Kronman
Journal:  Biochem J       Date:  1979-11-01       Impact factor: 3.857

8.  Leishmanicidal activities of novel synthetic furoxan and benzofuroxan derivatives.

Authors:  Luiz Antônio Dutra; Letícia de Almeida; Thais G Passalacqua; Juliana Santana Reis; Fabio A E Torres; Isabel Martinez; Rosangela Gonçalves Peccinini; Chung Man Chin; Konstantin Chegaev; Stefano Guglielmo; Roberta Fruttero; Marcia A S Graminha; Jean Leandro dos Santos
Journal:  Antimicrob Agents Chemother       Date:  2014-06-09       Impact factor: 5.191

9.  Cross-species chemogenomic profiling reveals evolutionarily conserved drug mode of action.

Authors:  Laura Kapitzky; Pedro Beltrao; Theresa J Berens; Nadine Gassner; Chunshui Zhou; Arthur Wüster; Julie Wu; M Madan Babu; Stephen J Elledge; David Toczyski; R Scott Lokey; Nevan J Krogan
Journal:  Mol Syst Biol       Date:  2010-12-21       Impact factor: 11.429

10.  Structural-Functional Analysis of 2,1,3-Benzoxadiazoles and Their N-oxides As HIV-1 Integrase Inhibitors.

Authors:  S P Korolev; O V Kondrashina; D S Druzhilovsky; A M Starosotnikov; M D Dutov; M A Bastrakov; I L Dalinger; D A Filimonov; S A Shevelev; V V Poroikov; Y Y Agapkina; M B Gottikh
Journal:  Acta Naturae       Date:  2013-01       Impact factor: 1.845

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