Literature DB >> 5676955

Autoimmune haemolytic anaemia and mefenamic acid therapy.

G L Scott, A B Myles, P A Bacon.   

Abstract

Three patients developed autoimmune haemolytic anaemia while being treated with mefenamic acid. In each case the autoimmune haemolytic anaemia was of the warm antibody gammaG type, and the antibodies had some rhesus specificity. All three patients recovered when the drug was withdrawn.Attempts to inhibit or enhance the activity of the antibody in vitro were unsuccessful.Direct antihuman globulin tests were made in.the red cells of 36 patients receiving long-term mefenamic acid therapy, but only one was found to be transitorily positive.

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Year:  1968        PMID： 5676955      PMCID： PMC1986458          DOI： 10.1136/bmj.3.5617.534

Source DB:  PubMed          Journal:  Br Med J        ISSN： 0007-1447


  7 in total

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Authors:  W J CAHILL; R D HILL; J JESSOP; P H KENDALL
Journal:  Ann Phys Med       Date:  1965-02

2.  Autoimmune haemolytic anaemia associated with alpha-methyldopa therapy.

Authors:  S M Worlledge; K C Carstairs; J V Dacie
Journal:  Lancet       Date:  1966-07-16       Impact factor: 79.321

3.  Incidence of a positive direct coombs test in patients on alpha-methyldopa.

Authors:  K C Carstairs; A Breckenridge; C T Dollery; S M Worlledge
Journal:  Lancet       Date:  1966-07-16       Impact factor: 79.321

4.  Mefenamic acid in rheumatoid arthritis.

Authors:  A B Myles; P A Bacon; K A Williams
Journal:  Ann Rheum Dis       Date:  1967-11       Impact factor: 19.103

5.  Methyldopa and haemolytic anaemia.

Authors:  W J Louis; A E Doyle; G Jerums; P Kincaid-Smith
Journal:  Med J Aust       Date:  1967-07-15       Impact factor: 7.738

6.  The nature of the alpha-methyldopa red-cell antibody.

Authors:  A F LoBuglio; J H Jandl
Journal:  N Engl J Med       Date:  1967-03-23       Impact factor: 91.245

7.  Mefenamic acid and flufenamic acid compared with aspirin and phenylbutazone in rheumatoid arthritis.

Authors:  D E Barnardo; H L Currey; R M Mason; W R Fox; M Weatherall
Journal:  Br Med J       Date:  1966-08-06
  7 in total
  8 in total

1.  Red cell antibodies and autoimmune haemolysis after treatment with azapropazone.

Authors:  D Chan-Lam; A W Thorburn; E A Chalmers; W H Watson; E J Fitzsimons
Journal:  Br Med J (Clin Res Ed)       Date:  1986-12-06

2.  Alveolitis and haemolytic anaemia induced by azapropazone.

Authors:  M K Albazzaz; J E Harvey; J N Hoffman; J A Siddorn
Journal:  Br Med J (Clin Res Ed)       Date:  1986-12-13

3.  Mefanamic acid-induced haemolytic anaemia.

Authors:  J M Jackson; J Quinlan; P Goatcher
Journal:  Br Med J       Date:  1970-05-02

4.  Haemolytic anaemia associated with mefenamic acid.

Authors:  J H Robertson; C C Kennedy; C M Hill
Journal:  Ir J Med Sci       Date:  1971-05       Impact factor: 1.568

5.  High mean red cell volume: its incidence and significance in routine haematology.

Authors:  R J Davidson; P J Hamilton
Journal:  J Clin Pathol       Date:  1978-05       Impact factor: 3.411

6.  A case of Stevens-Johnson syndrome, cholestatic hepatitis and haemolytic anaemia associated with use of mefenamic acid.

Authors:  J C Chan; F M Lai; J A Critchley
Journal:  Drug Saf       Date:  1991 May-Jun       Impact factor: 5.606

Review 7.  Aspirin, paracetamol and non-steroidal anti-inflammatory drugs. A comparative review of side effects.

Authors:  P D Fowler
Journal:  Med Toxicol Adverse Drug Exp       Date:  1987 Sep-Oct

Review 8.  Fatal fulminant autoimmune haemolytic anaemia associated with tolmetin use and gastric carcinoma. Case report and literature review.

Authors:  J R Larsen; J W Becher
Journal:  Drug Saf       Date:  1993-02       Impact factor: 5.606
  8 in total

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