Literature DB >> 567529

Filtration effect of endothelial fenestrations on chylomicron transport in neonatal rat liver sinusoids.

M Naito, E Wisse.   

Abstract

The function of endothelial fenestrations in the control of the passage of chylomicrons from the blood to the liver parenchymal cells was studied ultrastructurally in neonatal rats. Measurement of circulating chylomicrons and endothelial fenestrations as well as chylomicrons in the space of Disse at 2--20 h after the onset of suckling revealed a substantial filtration effect of endothelial fenestrations on chylomicrons larger than 250 nm in diameter. Direct uptake of chylomicrons by parenchymal cells was observed to occur by pinocytosis; Kupffer cells endocytosed only very few chylomicrons, and endothelial cells were inactive in this respect.

Entities:  

Mesh：

Substances：

Year:  1978        PMID： 567529     DOI： 10.1007/bf00219553

Source DB:  PubMed          Journal:  Cell Tissue Res        ISSN： 0302-766X            Impact factor:   5.249


  30 in total

1.  [Electron microscopic detection of fat particles in Disse's space].

Authors:  R CAESAR
Journal:  Z Zellforsch Mikrosk Anat       Date:  1961

2.  Phagocytosis of gelatinized "R. E. test lipid emulsion" by Kupffer cells: electronmicroscopic observations.

Authors:  H Tonaki; T M Saba; L W Mayron; E Kaplan
Journal:  Exp Mol Pathol       Date:  1976-10       Impact factor: 3.362

3.  Kupffer cell reactions in rat liver under various conditions as observed in the electron microscope.

Authors:  E Wisse
Journal:  J Ultrastruct Res       Date:  1974-03

4.  Effect of the administration of large doses of vitamin A on the fine structure of rat liver with special reference to changes in the fat-storing cell.

Authors:  K Kobayashi; Y Takahashi
Journal:  Arch Histol Jpn       Date:  1971-12

5.  Size and lipid composition of chylomicrons of different Svedberg units of flotation.

Authors:  R Fraser
Journal:  J Lipid Res       Date:  1970-01       Impact factor: 5.922

6.  [The fine structural changes in the liver cells of rats of various stages of development and the effect of whole body irradiation on the substructure of the liver of newborn rats].

Authors:  H Franke; E Goetze
Journal:  Acta Biol Med Ger       Date:  1967

7.  "Sternzellen" in the liver: perisinusoidal cells with special reference to storage of vitamin A.

Authors:  K Wake
Journal:  Am J Anat       Date:  1971-12

8.  Effects of parenteral nutrition with lipids on the human liver. An electron-microscopic study.

Authors:  U J van Haelst; R C Sengers
Journal:  Virchows Arch B Cell Pathol       Date:  1976-12-02

9.  The metabolism of chylomicron cholesteryl ester in rat liver. A combined radioautographic-electron microscopic and biochemical study.

Authors:  O Stein; Y Stein; D S Goodman; N H Fidge
Journal:  J Cell Biol       Date:  1969-12       Impact factor: 10.539

10.  Lipid synthesis, intracellular transport, storage, and secretion. I. Electron microscopic radioautographic study of liver after injection of tritiated palmitate or glycerol in fasted and ethanol-treated rats.

Authors:  O Stein; Y Stein
Journal:  J Cell Biol       Date:  1967-05       Impact factor: 10.539
View more
  19 in total

Review 1.  Scavenger functions of the liver endothelial cell.

Authors:  B Smedsrød; H Pertoft; S Gustafson; T C Laurent
Journal:  Biochem J       Date:  1990-03-01       Impact factor: 3.857

2.  Three-dimensional structure of endothelial cells in hepatic sinusoids of the rat as revealed by the Golgi method.

Authors:  K Wake; K Motomatsu; C Dan; K Kaneda
Journal:  Cell Tissue Res       Date:  1988-09       Impact factor: 5.249

3.  Biodistribution and clearance of magnetoelectric nanoparticles for nanomedical applications using energy dispersive spectroscopy.

Authors:  Ali Hadjikhani; Alexa Rodzinski; Ping Wang; Abhignyan Nagesetti; Rakesh Guduru; Ping Liang; Carolyn Runowicz; Sina Shahbazmohamadi; Sakhrat Khizroev
Journal:  Nanomedicine (Lond)       Date:  2017-07-14       Impact factor: 5.307

Review 4.  Cell biology of liver endothelial and Kupffer cells.

Authors:  B Smedsrød; P J De Bleser; F Braet; P Lovisetti; K Vanderkerken; E Wisse; A Geerts
Journal:  Gut       Date:  1994-11       Impact factor: 23.059

Review 5.  The role of the liver in clearance of glycoproteins from the general circulation, with special reference to intestinal alkaline phosphatase.

Authors:  D K Meijer; H B Scholtens; M J Hardonk
Journal:  Pharm Weekbl Sci       Date:  1982-06-25

6.  Primary cultures of endothelial cells of the rat liver: a model for ultrastructural and functional studies.

Authors:  A M de Leeuw; R J Barelds; R de Zanger; D L Knook
Journal:  Cell Tissue Res       Date:  1982       Impact factor: 5.249

7.  A scanning electron microscopic study of the liver of the monkey Macaca speciosa. I. Vascular system of the hepatic lobule.

Authors:  F J Vonnahme; O Müller
Journal:  Cell Tissue Res       Date:  1981       Impact factor: 5.249

8.  High perfusion pressure damages the sieving ability of sinusoidal endothelium in rat livers.

Authors:  R Fraser; L M Bowler; W A Day; B Dobbs; H D Johnson; D Lee
Journal:  Br J Exp Pathol       Date:  1980-04

9.  Distribution of heme oxygenase isoforms in rat liver. Topographic basis for carbon monoxide-mediated microvascular relaxation.

Authors:  N Goda; K Suzuki; M Naito; S Takeoka; E Tsuchida; Y Ishimura; T Tamatani; M Suematsu
Journal:  J Clin Invest       Date:  1998-02-01       Impact factor: 14.808

10.  Nicotine decreases the porosity of the rat liver sieve: a possible mechanism for hypercholesterolaemia.

Authors:  R Fraser; S A Clark; W A Day; F E Murray
Journal:  Br J Exp Pathol       Date:  1988-06
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.