Literature DB >> 567304

Penicillamine-induced myasthenia gravis associated with antibodies to acetylcholine receptor.

A S Russell, J M Lindstrom.   

Abstract

A woman with rheumatoid arthritis was treated with penicillamine and developed myasthenia gravis. This drug-induced disease was associated with characteristic autoantibodies to acetycholine receptor. After discontinuing the drug, her symptoms improved and the antibody titers fell. Penicillamine is now being used much more frequently in the treatment of rheumatoid arthritis and it is likely that this complication will become more prevalent.

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Year:  1978        PMID： 567304     DOI： 10.1212/wnl.28.8.847

Source DB:  PubMed          Journal:  Neurology        ISSN： 0028-3878            Impact factor:   9.910


  8 in total

Review 1.  Drug interactions with neuromuscular blockers.

Authors:  S Feldman; L Karalliedde
Journal:  Drug Saf       Date:  1996-10       Impact factor: 5.606

Review 2.  The main immunogenic region (MIR) of the nicotinic acetylcholine receptor and the anti-MIR antibodies.

Authors:  S J Tzartos; M T Cung; P Demange; H Loutrari; A Mamalaki; M Marraud; I Papadouli; C Sakarellos; V Tsikaris
Journal:  Mol Neurobiol       Date:  1991       Impact factor: 5.590

3.  Fine antigenic specificities of antibodies in sera from patients with D-penicillamine-induced myasthenia gravis.

Authors:  S J Tzartos; E Morel; A Efthimiadis; A F Bustarret; J D'Anglejan; A A Drosos; H A Moutsopoulos
Journal:  Clin Exp Immunol       Date:  1988-10       Impact factor: 4.330

Review 4.  Tissue-specific antibodies in myasthenia gravis.

Authors:  A Vincent
Journal:  J Clin Pathol Suppl (R Coll Pathol)       Date:  1979

Review 5.  Induction of auto-immune syndromes by penicillamine therapy in rheumatoid arthritis and other diseases.

Authors:  I A Jaffe
Journal:  Springer Semin Immunopathol       Date:  1981

6.  Anti-acetylcholine receptor antibodies.

Authors:  A Vincent; J Newsom Davis
Journal:  J Neurol Neurosurg Psychiatry       Date:  1980-07       Impact factor: 10.154

Review 7.  Ocular myasthenia gravis after D-penicillamine administration.

Authors:  L J Katz; R L Lesser; J R Merikangas; J P Silverman
Journal:  Br J Ophthalmol       Date:  1989-12       Impact factor: 4.638

8.  HLA antigens and acetylcholine receptor antibodies in penicillamine induced myasthenia gravis.

Authors:  M J Garlepp; R L Dawkins; F T Christiansen
Journal:  Br Med J (Clin Res Ed)       Date:  1983-01-29
  8 in total

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