Literature DB >> 566673

Influence of treatment duration on audiogenic seizure susceptibility during barbiturate withdrawal in rats.

D H McGee, W M Bourn.   

Abstract

Barbiturate withdrawal seizure susceptibility in rats increased with increasing duration of treatment during a 15-day treatment period in which the animals were given an i.p. dose of sodium barbital every 12 h. This method of producing dependence has clear advantages over previously described methods.

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Year:  1978        PMID: 566673     DOI: 10.1007/bf01939675

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  5 in total

1.  Acute tolerance to barbiturate in the rat.

Authors:  M J Turnbull; J W Watkins
Journal:  Eur J Pharmacol       Date:  1976-03       Impact factor: 4.432

2.  Gamma-aminobutyric acid and the barbiturate abstinence syndrome in rats.

Authors:  J Crossland; M J Turnbull
Journal:  Neuropharmacology       Date:  1972-09       Impact factor: 5.250

3.  Role of brain norepinephrine in audiogenic seizure in the rat.

Authors:  P C Jobe; A L Picchioni; L Chin
Journal:  J Pharmacol Exp Ther       Date:  1973-01       Impact factor: 4.030

4.  Barbiturate withdrawal in white rats.

Authors:  C F Essig
Journal:  Int J Neuropharmacol       Date:  1966-01

5.  The rapid development of physical dependence on barbiturates.

Authors:  J H Jaffe; S K Sharpless
Journal:  J Pharmacol Exp Ther       Date:  1965-10       Impact factor: 4.030

  5 in total

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