Literature DB >> 5662988

Copper and manganese concentrations in biliary cirrhosis of liver.

M Worwood, D M Taylor, A H Hunt.   

Abstract

The presence of large amounts of copper in the liver in primary biliary cirrhosis has been confirmed; a similar increase is not found in cases of long-standing extrahepatic biliary obstruction. The serum caeruloplasmin levels are raised in primary and secondary biliary cirrhosis, but this increase does not appear to be related to the degree of increase of hepatic copper. The manganese content of the liver is slightly raised in both these conditions.The reason for the increased metal content in these circumstances cannot yet be determined, and the effects are not yet understood.

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Year:  1968        PMID： 5662988      PMCID： PMC1991199          DOI： 10.1136/bmj.3.5614.344

Source DB:  PubMed          Journal:  Br Med J        ISSN： 0007-1447


  12 in total

1.  Studies on copper metabolism. XXIII. Portal (Laennec's) cirrhosis of the liver.

Authors:  C J GUBLER; H BROWN; H MARKOWITZ; G E CARTWRIGHT; M M WINTROBE
Journal:  J Clin Invest       Date:  1957-08       Impact factor: 14.808

2.  Demonstration of copper and acid phosphatase activity in hepatocyte lysosomes in experimental copper toxicity.

Authors:  S Goldfischer
Journal:  Nature       Date:  1967-07-01       Impact factor: 49.962

3.  Copper distribution in the neonatal rat.

Authors:  G W Evans; R E Wiederanders
Journal:  Am J Physiol       Date:  1967-11

4.  The concentrations of cobalt, copper, iron and zinc in some normal human tissues as determined by neutron-activation analysis.

Authors:  R M Parr; D M Taylor
Journal:  Biochem J       Date:  1964-06       Impact factor: 3.857

5.  Role of liver in regulating distribution and excretion of manganese.

Authors:  P S Papavasiliou; S T Miller; G C Cotzias
Journal:  Am J Physiol       Date:  1966-07

6.  Electron probe microanalysis of liver in Wilson's disease. Simultaneous assay for copper and for lead deposited by acid phosphatase activity in lysosomes.

Authors:  S Goldfischer; J Moskal
Journal:  Am J Pathol       Date:  1966-02       Impact factor: 4.307

7.  A method for the demonstration of copper under the electron microscope.

Authors:  P J Scheuer; M E Thorpe; P Marriott
Journal:  J Histochem Cytochem       Date:  1967-05       Impact factor: 2.479

8.  Studies on the pathogenesis of hepatolenticular degeneration. I. Acid phosphatase activity in copper-loaded rat livers.

Authors:  R R Lindquist
Journal:  Am J Pathol       Date:  1967-10       Impact factor: 4.307

9.  Factors influencing serum ceruloplasmin levels in normal individuals.

Authors:  D W Cox
Journal:  J Lab Clin Med       Date:  1966-12

10.  Trace metal patterns in disease states. II. Copper storage diseases, with consideration of juvenile cirrhosis, Wilson's disease, and hepatic copper of the newborn.

Authors:  E M BUTT; R E NUSBAUM; T C GILMOUR; S L DIDIO
Journal:  Am J Clin Pathol       Date:  1958-12       Impact factor: 2.493
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  8 in total

1.  Manganese transport and toxicity in polarized WIF-B hepatocytes.

Authors:  Khristy J Thompson; Jennifer Hein; Andrew Baez; Jose Carlo Sosa; Marianne Wessling-Resnick
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2018-05-24       Impact factor: 4.052

2.  Orthotopic liver transplantation for Wilson's disease.

Authors:  R S DuBois; D O Rodgerson; G Martineau; G Shroter; G Giles; J Lilly; C G Halgrimson; T E Starzl; I Sternlieb; I H Scheinberg
Journal:  Lancet       Date:  1971-03-13       Impact factor: 79.321

3.  [D-penicillamine in the treatment of pulmonary fibrosis (author's transl)].

Authors:  K Gross; K Unholtz
Journal:  Pneumonologie       Date:  1973-08-24

4.  Demonstration of an intracellular copper-binding protein by orcein staining in long-standing cholestatic liver diseases.

Authors:  M Salaspuro; P Sipponen
Journal:  Gut       Date:  1976-10       Impact factor: 23.059

Review 5.  Serology of primary biliary cirrhosis.

Authors:  P A Berg; H Baum
Journal:  Springer Semin Immunopathol       Date:  1980-12

6.  Copper chelation therapy in intrahepatic cholestasis of childhood.

Authors:  J Evans; H Zerpa; L Nuttall; M Boss; S Sherlock
Journal:  Gut       Date:  1983-01       Impact factor: 23.059

7.  Correlation of Trace Elements in Patients of Chronic Liver Disease with Respect to Child- Turcotte- Pugh Scoring System.

Authors:  Amit Agarwal; Shilpa Avarebeel; Narendra S Choudhary; Mohan Goudar; C J Tejaswini
Journal:  J Clin Diagn Res       Date:  2017-09-01

8.  Hepatic copper accumulation in primary biliary cirrhosis.

Authors:  G D Benson
Journal:  Yale J Biol Med       Date:  1979 Jan-Feb
  8 in total

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