Literature DB >> 565921

Introduction of ribonucleic acids into cells by means of liposomes.

G J Dimitraidis.   

Abstract

A method of ultramicroinjection of nucleic acids into cultured cells by means of liposomes is described. Messenger RNA, ribosomal RNA and transfer RNA were entrapped in large unilamellar liposomes and subsequently the liposomes were fused with cells. The uptake of RNA by the cells was stimulated 6--8 times by our method. Possible applications of microinjection of RNA by means of liposomes are discussed.

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Year:  1978        PMID： 565921      PMCID： PMC342085          DOI： 10.1093/nar/5.4.1381

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  11 in total

1.  Use of erythrocyte ghosts for injection of substances into animal cells by cell fusion.

Authors:  M Furusawa; M Yamaizumi; T Nishimura; T Uchida; Y Okada
Journal:  Methods Cell Biol       Date:  1976       Impact factor: 1.441

2.  Injection of foreign substances into single cells by cell fusion.

Authors:  M Furusawa; T Nishimura; M Yamaizumi; Y Okada
Journal:  Nature       Date:  1974-05-31       Impact factor: 49.962

3.  Inhibition by interferon of SV40 tumor antigen formation in cells injected with SV40 cRNA transcribed in vitro.

Authors:  G Brandner; N Mueller; A Graessmann; M Graessmann; J Niebel; H Hoffmann
Journal:  FEBS Lett       Date:  1974-03-01       Impact factor: 4.124

4.  Rabbit haemoglobin synthesis in frog cells: the translation of reticulocyte 9 s RNA in frog oocytes.

Authors:  C D Lane; G Marbaix; J B Gurdon
Journal:  J Mol Biol       Date:  1971-10-14       Impact factor: 5.469

5.  Targeting of drugs.

Authors:  G Gregoriadis
Journal:  Nature       Date:  1977-02-03       Impact factor: 49.962

6.  Lipid vesicles as carriers for introducing biologically active materials into cells.

Authors:  G Poste; D Papahadjopoulos; W J Vail
Journal:  Methods Cell Biol       Date:  1976       Impact factor: 1.441

7.  Induction of protein synthesis in mitochondria by exogenous RNA. Synthesis of rabbit globin by isolated mitochondria of Tetrahymena pyriformis.

Authors:  G J Dimitriadis; J G Georgatsos
Journal:  FEBS Lett       Date:  1974-09-15       Impact factor: 4.124

8.  Cochleate lipid cylinders: formation by fusion of unilamellar lipid vesicles.

Authors:  D Papahadjopoulos; W J Vail; K Jacobson; G Poste
Journal:  Biochim Biophys Acta       Date:  1975-07-03

9.  Synthesis of tobacco mosaic virus coat protein following migration of viral RNA into isolated mouse liver mitochondria.

Authors:  G J Dimitriadis; J G Georgatsos
Journal:  Nucleic Acids Res       Date:  1975-10       Impact factor: 16.971

10.  "Ultramicroinjection" of macromolecules or small particles into animal cells. A new technique based on virus-induced cell fusion.

Authors:  A Loyter; N Zakai; R G Kulka
Journal:  J Cell Biol       Date:  1975-08       Impact factor: 10.539
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  3 in total

1.  Entrapment of plasmid DNA in liposomes.

Authors:  G J Dimitriadis
Journal:  Nucleic Acids Res       Date:  1979-06-25       Impact factor: 16.971

2.  Entrapment of human leukocyte interferon in the aqueous interstices of liposomes.

Authors:  P Anderson; J Vilcek; G Weissmann
Journal:  Infect Immun       Date:  1981-03       Impact factor: 3.441

Review 3.  Mesenchymal Stem Cells Engineered by Nonviral Vectors: A Powerful Tool in Cancer Gene Therapy.

Authors:  Yuan Ding; Chenyang Wang; Zhongquan Sun; Yingsheng Wu; Wanlu You; Zhengwei Mao; Weilin Wang
Journal:  Pharmaceutics       Date:  2021-06-21       Impact factor: 6.321
  3 in total

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