Literature DB >> 5654209

Irreversible enzyme inhibitors. CXIV. Proteolytic enzymes. IV. Additional active-site-directed irreversible inhibitors of alpha-chymotrypsin derived from phenoxyacetamides bearing a terminal sulfonyl fluoride.

B R Baker, J A Hurlbut.   

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Year:  1968        PMID： 5654209     DOI： 10.1021/jm00308a010

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  4 in total

1.  SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase.

Authors:  Qinheng Zheng; Jordan L Woehl; Seiya Kitamura; Diogo Santos-Martins; Christopher J Smedley; Gencheng Li; Stefano Forli; John E Moses; Dennis W Wolan; K Barry Sharpless
Journal:  Proc Natl Acad Sci U S A       Date:  2019-09-04       Impact factor: 11.205

2.  Diversity Oriented Clicking (DOC): Divergent Synthesis of SuFExable Pharmacophores from 2-Substituted-Alkynyl-1-Sulfonyl Fluoride (SASF) Hubs.

Authors:  Christopher J Smedley; Gencheng Li; Andrew S Barrow; Timothy L Gialelis; Marie-Claire Giel; Alessandra Ottonello; Yunfei Cheng; Seiya Kitamura; Dennis W Wolan; K Barry Sharpless; John E Moses
Journal:  Angew Chem Int Ed Engl       Date:  2020-06-04       Impact factor: 15.336

3.  Arylfluorosulfates Inactivate Intracellular Lipid Binding Protein(s) through Chemoselective SuFEx Reaction with a Binding Site Tyr Residue.

Authors:  Wentao Chen; Jiajia Dong; Lars Plate; David E Mortenson; Gabriel J Brighty; Suhua Li; Yu Liu; Andrea Galmozzi; Peter S Lee; Jonathan J Hulce; Benjamin F Cravatt; Enrique Saez; Evan T Powers; Ian A Wilson; K Barry Sharpless; Jeffery W Kelly
Journal:  J Am Chem Soc       Date:  2016-06-02       Impact factor: 15.419

Review 4.  Arylfluorosulfate-Based Electrophiles for Covalent Protein Labeling: A New Addition to the Arsenal.

Authors:  Pablo Martín-Gago; Christian A Olsen
Journal:  Angew Chem Int Ed Engl       Date:  2018-10-26       Impact factor: 15.336
  4 in total

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