Literature DB >> 5651209

Acetylation of human serum albumin by acetylsalicylic acid.

D Hawkins, R N Pinckard, R S Farr.   

Abstract

Human serum albumin is acetylated when exposed to acetylsalicylic acid (aspirin) under physiologic conditions in vitro. Indications are that a similar phenomenon occurs in vivo after ingestion of aspirin.

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Year:  1968        PMID： 5651209     DOI： 10.1126/science.160.3829.780

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  23 in total

1.  The esterase-like activity of serum albumin may be due to cholinesterase contamination.

Authors:  N Chapuis; C Brühlmann; M Reist; P A Carrupt; J M Mayer; B Testa
Journal:  Pharm Res       Date:  2001-10       Impact factor: 4.200

Review 2.  Disease-induced variations in plasma protein levels. Implications for drug dosage regimens (Part II).

Authors:  R Zini; P Riant; J Barré; J P Tillement
Journal:  Clin Pharmacokinet       Date:  1990-09       Impact factor: 6.447

Review 3.  Diseases and drug protein binding.

Authors:  J P Tillement; F Lhoste; J F Giudicelli
Journal:  Clin Pharmacokinet       Date:  1978 Mar-Apr       Impact factor: 6.447

4.  The effect of octanoic acid on the binding of the enantiomers of ibuprofen and naproxen to human serum albumin: a chromatographic implication.

Authors:  V K Cheruvallath; C M Riley; S R Narayanan; S Lindenbaum; J H Perrin
Journal:  Pharm Res       Date:  1996-01       Impact factor: 4.200

5.  Discovery of diflunisal.

Authors:  J Hannah; W V Ruyle; H Jones; A R Matzuk; K W Kelly; B E Witzel; W J Holtz; R W Houser; T Y Shen; L H Sarett
Journal:  Br J Clin Pharmacol       Date:  1977-02       Impact factor: 4.335

6.  Divergent effects of aspirin and salicylate on glucose and glycogen metabolism in human platelets.

Authors:  J C Doery; J Hirsh
Journal:  Experientia       Date:  1971-05-15

7.  [Prevention of thrombosis using aspirin? nfluence of acetylsalicylic acid on thrombocyte aggregation in vitro and in vivo].

Authors:  I Scharrer; M Schepping; K Breddin
Journal:  Klin Wochenschr       Date:  1969-12-15

8.  Reaction of human albumin with aspirin in vitro: mass spectrometric identification of acetylated lysines 199, 402, 519, and 545.

Authors:  Mariya S Liyasova; Lawrence M Schopfer; Oksana Lockridge
Journal:  Biochem Pharmacol       Date:  2009-10-27       Impact factor: 5.858

9.  Gel-filtered human platelets. Ultrastructure, function, and role of proteins in inhibition of aggregation by aspirin.

Authors:  K M Fine; P C Ashbrook; L P Brigden; J E Maldonado; P Didishelm
Journal:  Am J Pathol       Date:  1976-07       Impact factor: 4.307

10.  Pseudo-esterase activity of human albumin: slow turnover on tyrosine 411 and stable acetylation of 82 residues including 59 lysines.

Authors:  Oksana Lockridge; Weihua Xue; Andrea Gaydess; Hasmik Grigoryan; Shi-Jian Ding; Lawrence M Schopfer; Steven H Hinrichs; Patrick Masson
Journal:  J Biol Chem       Date:  2008-06-24       Impact factor: 5.157
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