Literature DB >> 5648266

LSD in mice: abnormalities in meiotic chromosomes.

N E Skakkebaek, J Philip, O J Rafaelsen.   

Abstract

Meiotic chromosomes of six mice injected with high doses of lysergic acid diethylamide (LSD-25) and of six controls were studied. Several breaks, gaps, and unidentifiable fragments were found in the treated but, with a few exceptions, not in the control animals. Secondary constrictions were more numerous in the treated than in the untreated mice. Possible consequences are discussed.

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Year:  1968        PMID: 5648266     DOI: 10.1126/science.160.3833.1246

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  7 in total

Review 1.  Progress in birth defects research.

Authors:  M R Bernfield
Journal:  Calif Med       Date:  1970-02

Review 2.  The chromosomal and teratogenic effects of lysergic acid diethylamide: a review of the current literature.

Authors:  R G Smart; K Bateman
Journal:  Can Med Assoc J       Date:  1968-10-26       Impact factor: 8.262

3.  Effect of LSD on mitotic and meiotic plant chromosomes.

Authors:  R S Sadasivaiah; G B Collins; D L Davis
Journal:  Chromosoma       Date:  1973       Impact factor: 4.316

4.  LSD induced genetic damage in barley.

Authors:  C S Kalia; M P Singh; H K Jain; R K Katiyar
Journal:  Chromosoma       Date:  1970       Impact factor: 4.316

5.  Rat and human chromosome studies after promazine medication.

Authors:  I C Roman
Journal:  Br Med J       Date:  1969-10-18

6.  Testing of LSD-25 and related compounds for possible effects on egg-laying capacity and egg-to-adult viability in Drosophila.

Authors:  C D Kastritsis; A Jacob-Stocker
Journal:  Experientia       Date:  1971-06

7.  Effect of LSD-25 on mitotic and meiotic chromosomes of mice and monkeys.

Authors:  J Egozcue; S Irwin
Journal:  Humangenetik       Date:  1969-10
  7 in total

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