Literature DB >> 5645409

Interaction of staphylococcal penicillinase and 6-[D(-)-alphaguanidino-phenylacetamido]-penicillanic acid.

E H Thiele, H J Robinson.   

Abstract

6[d(-)-alpha-Guanidinophenylacetamido]-penicillanic acid was shown to be significantly hydrolyzed by only one of six preparations of staphylococcal penicillinase. This penicillin analogue is a stronger penicillinase inactivator than are nafcillin and methicillin, which were not significantly hydrolyzed by the enzyme.

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Year:  1968        PMID： 5645409      PMCID： PMC547384          DOI： 10.1128/am.16.2.228-231.1968

Source DB:  PubMed          Journal:  Appl Microbiol        ISSN： 0003-6919


  12 in total

1.  INHIBITION OF PENICILLINASES FROM GRAM-POSITIVE AND GRAM-NEGATIVE BACTERIA BY SUBSTRATE ANALOGUES.

Authors:  J M HAMILTON-MILLER; J T SMITH
Journal:  Nature       Date:  1964-03-07       Impact factor: 49.962

2.  PURIFICATION AND PROPERTIES OF THE EXOPENICILLINASE FROM STAPHYLOCOCCUS AUREUS.

Authors:  M H RICHMOND
Journal:  Biochem J       Date:  1963-09       Impact factor: 3.857

3.  STUDIES ON PENICILLINASE PRODUCED BY A STRAIN OF STAPHYLOCOCCUS AUREUS.

Authors:  F R BATCHELOR; J CAMERON-WOOD; E B CHAIN; G N ROLINSON
Journal:  Proc R Soc Lond B Biol Sci       Date:  1963-10-22

4.  The nature of resistance of a penicillin to hydrolysis by pencillinase.

Authors:  N CITRI; N GARBER
Journal:  J Pharm Pharmacol       Date:  1962-12       Impact factor: 3.765

5.  Behaviour of some derivatives of 7-aminocephalosporanic acid and 6-aminopenicillanic acidas substrates, inhibitors and inducers of penicillinases.

Authors:  B CROMPTON; M JAGO; K CRAWFORD; G G NEWTON; E P ABRAHAM
Journal:  Biochem J       Date:  1962-04       Impact factor: 3.857

6.  Inactivation of staphylococcal penicillinase by reaction with resistant penicillins.

Authors:  A GOUREVITCH; T A PURSIANO; J LEIN
Journal:  Nature       Date:  1962-08-04       Impact factor: 49.962

7.  Bacteriological studies on a new penicillin-BRL. 1241.

Authors:  G N ROLINSON; S STEVENS; F R BATCHELOR; J C WOOD; E B CHAIN
Journal:  Lancet       Date:  1960-09-10       Impact factor: 79.321

8.  The interaction of penicillinase with penicillins. IV. Structural aspects of catalytic and non-catalytic interactions.

Authors:  N Citri; N Zyk
Journal:  Biochim Biophys Acta       Date:  1965-06-22

9.  Syntheses of guanidino-substituted penicillins and cephalosporins.

Authors:  W J Leanza; B G Christensen; E F Rogers; A A Patchett
Journal:  Nature       Date:  1965-09-25       Impact factor: 49.962

10.  Staphylococcal penicillinase. I. Inhibition and stimulation of activity.

Authors:  A K SAZ; D L LOWERY; L J JACKSON
Journal:  J Bacteriol       Date:  1961-08       Impact factor: 3.490
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