Literature DB >> 564367

Anticomplementary properties of 043/63 and 043/13 two new antiinflammatory drugs.

S Rosini, V Mazzoncini.   

Abstract

The anticomplementary properties of two indandione derivatives were studied in vitro on fresh human serum and in vivo on rabbits. In vitro the two substances block immunohemolysis and have direct effect on serum complement activity. One substance blocks the activation of the first complement component and the other the fourth complement component. In vivo, single doses, lower or block complement activity of rabbit serum.

Entities:  

Mesh:

Substances:

Year:  1977        PMID: 564367

Source DB:  PubMed          Journal:  J Hyg Epidemiol Microbiol Immunol        ISSN: 0022-1732


  1 in total

1.  Anti-complement activity in a series of substituted 2-aryl-1,3-indandiones; absence of correlation with the anti-carrageenan oedema effects.

Authors:  H van der Goot; H Timmerman; S S Asghar; A H Siddiqui
Journal:  Agents Actions       Date:  1984-10
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.