Literature DB >> 564053

Reduction by thiopental of the slow-channel-mediated action potential of canine papillary muscle.

Y Ikemoto.   

Abstract

The negative inotropic effect of thiopental was examined on the canine papillary muscle. The slow-channel-mediated action potential was induced by 5mM of caffeine in high-K (27 mM) Tyrode solution. The drug reduced the slow action potential and the twitch tension, suggesting a reduction in the slow inward current.

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Year:  1977        PMID： 564053     DOI： 10.1007/bf01063865

Source DB:  PubMed          Journal:  Pflugers Arch        ISSN： 0031-6768            Impact factor:   3.657


  8 in total

1.  The mechanism of the effects of sodium pentobarbital and norepinephrine on isolated cardiac muscle.

Authors:  E E DANIEL; P K JOHNSTON; J G FOULKS
Journal:  Arch Int Pharmacodyn Ther       Date:  1962-07-01

2.  The effect of cyclopropane, diethyl ether, nitrous oxide, thiopental, and hydrogen ion concentration on the myocardial dunction of the dog heart-lung preparation.

Authors:  H L PRICE; M HELRICH
Journal:  J Pharmacol Exp Ther       Date:  1955-10       Impact factor: 4.030

3.  Slow Ca2+ and Na+ responses induced by isoproterenol and methylxanthines in isolated perfused guinea pig hearts exposed to elevated K+.

Authors:  J A Schneider; N Sperelakis
Journal:  J Mol Cell Cardiol       Date:  1975-04       Impact factor: 5.000

4.  Barbiturates block calcium uptake by stimulated and potassium-depolarized rat sympathetic ganglia.

Authors:  M P Blaustein
Journal:  J Pharmacol Exp Ther       Date:  1976-01       Impact factor: 4.030

Review 5.  Divalent cations as charge carriers in excitable membranes.

Authors:  H Reuter
Journal:  Prog Biophys Mol Biol       Date:  1973       Impact factor: 3.667

6.  The negative inotropic effect of barbiturates on the heart of newborn and adult guinea-pigs.

Authors:  H Effendi; A Versprille; M E Wise
Journal:  Arch Int Pharmacodyn Ther       Date:  1974-05

7.  Anesthetic blocking of nerve membrane conductances by internal and external applications.

Authors:  T Narahashi; J W Moore; R N Poston
Journal:  J Neurobiol       Date:  1969

8.  The active form of pentobarbital in squid giant axons.

Authors:  T Narahashi; D T Frazier; T Deguchi; C A Cleaves; M C Ernau
Journal:  J Pharmacol Exp Ther       Date:  1971-04       Impact factor: 4.030
  8 in total
  2 in total

1.  Thiopentone inhibits beta-adrenergic responses in myocardial tissue.

Authors:  T A Thurston; B P Mathew
Journal:  Can J Anaesth       Date:  1995-10       Impact factor: 5.063

2.  Lack of effects of d-tubocurarine and pancuronium on the slow action potential of the guinea pig papillary muscle.

Authors:  H Arimura; Y Ikemoto; T Ito; J Yoshitake
Journal:  Can Anaesth Soc J       Date:  1985-09
  2 in total

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