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Literature DB >> 5634913

Crystal and molecular structure of adenosine 3',5'-cyclic phosphate.

K Watenpaugh, J Dow, L H Jensen, S Furberg.

Abstract

The structure of adenosine 3',5'-cyclic phosphate has been determined by single-crystal x-ray diffraction. The two molecules in the asymmetric unit show different conformation about the glycosidic bond, while other structural details are essentially the same. The furanose rings are puckered with the C(4') atom out of the best four-atom plane. The bond lengths and angles appear to be normal.

Entities: Chemical

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Year: 1968 PMID： 5634913 DOI： 10.1126/science.159.3811.206

Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728

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Cited

11 in total

1. Tumor-inhibiting properties of the neutral P-O-ethyl ester of adenosine 3':5'-monophosphate in correlation with its crystal and molecular structure.

Authors: F A Cotton; R G Gillen; R N Gohil; E E Hazen; C R Kirchner; J Nagyvary; J P Rouse; A G Stanislowski; J D Stevens; P W Tucker
Journal: Proc Natl Acad Sci U S A Date: 1975-04 Impact factor: 11.205

10. Mechanism for transcriptional action of cyclic AMP in Escherichia coli: entry into DNA to disrupt DNA secondary structure.

Authors: R H Ebright; J R Wong
Journal: Proc Natl Acad Sci U S A Date: 1981-07 Impact factor: 11.205

Crystal and molecular structure of adenosine 3',5'-cyclic phosphate.

1. Tumor-inhibiting properties of the neutral P-O-ethyl ester of adenosine 3':5'-monophosphate in correlation with its crystal and molecular structure.

2. Structural studies on the two forms of 8-bromo-2',3'-O-isopropylideneadenosine.

3. A novel guanine-guanine base pairing: crystal structure of a complex between 7-methylguanosine and its iodide.

4. The crystal and molecular structure of 2'-deoxy-2'-fluoroinosine monohydrate.

5. The dimensions and shapes of the furanose rings in nucleic acids.

6. Radioimmunoassay for the measurement of adenosine 3',5'-cyclic phosphate.

7. Synthesis and properties of some cyclic AMP alkyl phosphotriesters.

8. Structural and energetic analysis of activation by a cyclic nucleotide binding domain.

9. Absolute configuration of Rp-uridine 3',5'-cyclic phosphorothioate.

10. Mechanism for transcriptional action of cyclic AMP in Escherichia coli: entry into DNA to disrupt DNA secondary structure.