Literature DB >> 5629323

Hereditary renal disease in a mutant strain of rats.

B B Lozzio, A I Chernoff, E R Machado, C B Lozzio.   

Abstract

Disease of the kidney developed in breeding stock of Gunn rats. The renal lesion is the result of a new mutation. The genetic defect is inherited as an autosomal dominant trait and is apparently lethal in the homozygous condition. The abnormality manifests itself as a congenital hydronephrosis with related cystic changes in the kidney.

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Year:  1967        PMID： 5629323     DOI： 10.1126/science.156.3783.1742

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  6 in total

1.  Renomedullary deficiency. A contributory factor in the pathogenesis of experimental renal hypertension.

Authors:  D Susic; J C Sparks; E A Machado
Journal:  Experientia       Date:  1976-03-15

2.  Spontaneously occurring renal disease in the guinea pig.

Authors:  T Takeda; A Grollman
Journal:  Am J Pathol       Date:  1970-07       Impact factor: 4.307

3.  Animal model of human disease. Hydronephrosis, agenesis of the renal medulla, arterial hypertension.

Authors:  D Kentera; D Susic; E Machado; B B Lozzio
Journal:  Am J Pathol       Date:  1977-05       Impact factor: 4.307

4.  The renin-angiotensin system in rats with hereditary hydronephrosis.

Authors:  D Susic; J C Sparks; D Kentera
Journal:  Pflugers Arch       Date:  1975-07-28       Impact factor: 3.657

5.  Steroid-induced polycystic kidneys in the newborn rat.

Authors:  J F Crocker; A G Stewart; J M Sparling; M E Bruneau
Journal:  Am J Pathol       Date:  1976-02       Impact factor: 4.307

6.  Glomerular polycystic kidney disease in a dog (blue merle collie).

Authors:  A Chalifoux; J B Phaneuf; M Olivieri; Y Gosselin
Journal:  Can Vet J       Date:  1982-12       Impact factor: 1.008
  6 in total

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