Literature DB >> 561963

Oral intake of morphine in selectively bred rats.

K P Satinder.   

Abstract

Oral intake of morphine was investigated in selectively bred strains of rats. It was possible to induce all the five genetic lines to consume morphine in distilled water. Withdrawal of morphine resulted in significant decrease in the body weights of all the genetic lines in both the experiments. Significant drug-preference behavior was found only in three genetic lines with a common characteristic of relatively high emotional reactivity as compared to the two lines not showing such a behavior.

Entities:  

Mesh：

Substances：

Year:  1977        PMID： 561963     DOI： 10.1016/0091-3057(77)90008-9

Source DB:  PubMed          Journal:  Pharmacol Biochem Behav        ISSN： 0091-3057            Impact factor:   3.533


  2 in total

1.  Differences in morphine reinforcement property in two inbred rat strains: associations with cortical receptors, behavioral activity, analgesia and the cataleptic effects of morphine.

Authors:  S K Sudakov; S R Goldberg; E V Borisova; L A Surkova; I V Turina; G I Elmer
Journal:  Psychopharmacology (Berl)       Date:  1993       Impact factor: 4.530

Review 2.  Opioids and behavior: genetic aspects.

Authors:  H R Frischknecht; B Siegfried; P G Waser
Journal:  Experientia       Date:  1988-06-15
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.