| Literature DB >> 561097 |
Abstract
A method is described which should permit determination of the order and spacing of genes on all human chromosomes by the analysis of just one set of man-mouse hybrid cells. This method is used to determine the map of 8 loci on human chromosome I. A comparison of the statistical maps of chromosome I and of the X-chromosome with the cytogenetic maps of these chromosomes at metaphase indicates that the statistically derived distances between genes are related to the amount of Giemsa light-band material between the genes.Entities:
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Year: 1977 PMID: 561097 DOI: 10.1242/jcs.25.1.39
Source DB: PubMed Journal: J Cell Sci ISSN: 0021-9533 Impact factor: 5.285