Fibrinolytic response of diabetics and non-diabetics to adrenaline.

The fibrinolytic response of 30 diabetic patients and 35 non-diabetics to 0.5 mg. subcutaneous adrenaline was measured, using the dilute clot lysis test. With the exception of two patients out of six who were taking phenformin, who had a depressed response, the diabetics showed a similar increase in fibrinolytic activity to the non-diabetics. The diabetics in this series did not tend to have longer spontaneous lysis times than the non-diabetics, although this type of comparison may not be valid.