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Literature DB >> 5602510

Use of Sephadex column chromatography in the assessment of thyroid status.

Abstract

A method is described for assessing thyroid status using Sephadex column chromatography of serum samples with added (125)I triiodothyronine. The method is simple and inexpensive. It gave a correct diagnostic result in 97% of 258 euthyroid, 90% of 80 hyperthyroid, 78% of 59 hypothyroid, and 67% of 50 euthyroid, ill patients. The principle of the method and its limitations are briefly discussed.

Entities: Chemical Disease Species

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Year: 1967 PMID： 5602510 PMCID： PMC473449 DOI： 10.1136/jcp.20.2.170

Source DB: PubMed Journal: J Clin Pathol ISSN： 0021-9746 Impact factor: 3.411

5 in total

1. Labeling of erythrocytes in vitro with radioiodine-tagged I-triiodothyronine as an index of thyroid function: an improved hematocrit correction.

Authors: R ADAMS; N SPECHT; I WOODWARF
Journal: J Clin Endocrinol Metab Date: 1960-10 Impact factor: 5.958

2. Serum proteins, including thyroxine-binding proteins, in maternal and foetal rabbits.

Authors: N B MYANT; C OSORIO
Journal: J Physiol Date: 1959-05-19 Impact factor: 5.182

3. The in vitro resin sponge uptake of triiodothyronine-I-131 from serum in thyroid disease and in pregnancy.

Authors: M L MITCHELL; A B HARDEN; M E O'ROURKE
Journal: J Clin Endocrinol Metab Date: 1960-11 Impact factor: 5.958

4. Proteins associated with the thyroid hormones.

Authors: J ROBBINS; J E RALL
Journal: Physiol Rev Date: 1960-07 Impact factor: 37.312

5. The thyroid hormone-plasma protein complex in man. II. A new in vitro method for study of uptake of labelled hormonal components by human erythrocytes.

Authors: A S FREEDBERG; M W HAMOLSKY; M STEIN
Journal: J Clin Endocrinol Metab Date: 1957-01 Impact factor: 5.958

5 in total

1. Evaluation of new kits for the assessment in vitro of thyroid function by determination of serum total thyroxine, free TBG capacity, and free thyroxine index Sephadex G-25 and 125I-labelled triiodothyronine and thyroxine.

Authors: P J Howorth; C G McKerron
Journal: J Clin Pathol Date: 1974-02 Impact factor: 3.411

2. Deletion of the long arms of chromosome 18 (46,XX,18q-) associated with absence of IgA and hypothyroidism in an adult.

Authors: M J Faed; R Whyte; C R Paterson; M McCathie; J Robertson
Journal: J Med Genet Date: 1972-03 Impact factor: 6.318