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Literature DB >> 560061

Primary bioassay of human tumor stem cells.

Abstract

A simple method has been developed to support human tumor stem cell colony growth in soft agar. The technique appears suitable for culture of a variety of neoplasms of differing histopathology. Tumor stem cell colonies arising from different types of cancer have differing growth characteristics and colony morphology. This bioassay should be suitable for clinical studies of effects of anticancer drugs or irradiation on human tumor stem cells.

Entities: Disease Species

Mesh：

Substances：
Culture Media

Year: 1977 PMID： 560061 DOI： 10.1126/science.560061

Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728

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Cited

516 in total

1. Inhibition of antibacterial activity of himastatin, a new antitumor antibiotic from Streptomyces hygroscopicus, by fatty acid sodium salts.

Authors: S W Mamber; K W Brookshire; B J Dean; R A Firestone; J E Leet; J A Matson; S Forenza
Journal: Antimicrob Agents Chemother Date: 1994-11 Impact factor: 5.191

2. Extreme drug resistance in primary brain tumors: in vitro analysis of 64 resection specimens.

Authors: Raymond I Haroun; Richard E Clatterbuck; M Christopher Gibbons; Peter C Burger; Ricardo Parker; John P Fruehauf; Henry Brem
Journal: J Neurooncol Date: 2002-06 Impact factor: 4.130

Review 3. Cancer stem cells: relevance to SCT.

Authors: T Lin; R J Jones; W Matsui
Journal: Bone Marrow Transplant Date: 2009-02-23 Impact factor: 5.483

4. A 3-dimensional tumor growth inhibition assay for testing monoclonal antibody cytotoxicity.

Authors: W Z Wei; R J Massey; G H Heppner
Journal: Cancer Immunol Immunother Date: 1985 Impact factor: 6.968

5. In vitro evaluation of anticancer drugs in relation to development of drug resistance in the human tumor clonogenic assay.

Authors: K Inoue; T Mukaiyama; I Mitsui; M Ogawa
Journal: Cancer Chemother Pharmacol Date: 1985 Impact factor: 3.333

6. Inhibition of protein synthesis, pulmonary localization and pulmonary tumour formation by drug-treated tumour cells as a means of predicting their chemosensitivity.

Authors: T Lai; B R Stonebridge; J Black; M O Symes
Journal: Clin Exp Metastasis Date: 1989 Jul-Aug Impact factor: 5.150

Primary bioassay of human tumor stem cells.

1. Inhibition of antibacterial activity of himastatin, a new antitumor antibiotic from Streptomyces hygroscopicus, by fatty acid sodium salts.

2. Extreme drug resistance in primary brain tumors: in vitro analysis of 64 resection specimens.

Review 3. Cancer stem cells: relevance to SCT.

4. A 3-dimensional tumor growth inhibition assay for testing monoclonal antibody cytotoxicity.

5. In vitro evaluation of anticancer drugs in relation to development of drug resistance in the human tumor clonogenic assay.

6. Inhibition of protein synthesis, pulmonary localization and pulmonary tumour formation by drug-treated tumour cells as a means of predicting their chemosensitivity.

Review 7. Inflammation and stem cells in gastrointestinal carcinogenesis.

Review 8. The human tumor cloning assay in cancer drug development. A review.

Review 9. The human tumor colony-forming chemosensitivity assay: a biological and clinical review.

10. Cytotoxicity of mitomycin C on clonogenic human carcinoma cells is not enhanced by hypoxia.